Ссылки1. Is increased dietary protein necessary or beneficial for individuals with a physically active lifestyle? Lemon PW. Nutr Rev. 1996 Apr;54(4 Pt 2):S169-75. 2. Food intake, nitrogen and energy balance in Polish weight lifters, during a training camp. Celejowa I, Homa M. Nutr Metab. 1970;12(5):259-74. 3. Protein requirements and muscle mass/strength changes during intensive training in novice bodybuilders. Lemon PW, Tarnopolsky MA, MacDougall JD, Atkinson SA. J Appl Physiol. 1992 Aug;73(2):767-75. 4. Do regular high protein diets have potential healthy risks on kidney function in athletes? Poortmans J. et al. Int J Sport Nutr Exer Metab 10:28-38 (2000) 5. Slow and fast dietary proteins differently modulate postprandial protein accretion. Yves Boirie et al. Proc. Natl. Acad. Sci. V.94 pp. 14930-35. December, 1997. 6. Valine May Be the First Limiting Branched-Chain Amino Acid in Egg Protein in Men Roya Riazi, Mahroukh Rafii. American Society for Nutritional Sciences J. Nutr. 133:3533-3539, November 2003. 7. A method of determining the biological value of protein. H H. Mitchell. Journal of Biological Chemistry. Received November 19, 1923. 8. Rafalski, H. and Nogal, E. Proceedings of 7th International Congress on Nutrition. 4: 307. Pergamon Press, London (1966). 9. Williams MH. Nutrition for Health, Fitness and Sport. 7th ed. New York: McGraw-Hill 2007. 10. Nutritional needs of elite athletes. Part I: Carbohydrate and fluid requirements. Tarnopolsky MA et al. Eur J Sport Sci 5: 3-14 2005. 11. Mechanisms of muscle fatigue in intense exercise. Green HJ. J Sports Sci. 1997 Jun;15(3):247-56. 12. Glycemic index and glycemic load in relation to changes in body weight, body fat distribution, and body composition in adult Danes. Hare-Bruun H, Flint A, Heitmann BL. Am J Clin Nutr. 2006 Oct;84(4):871-9; quiz 952-3. 13. Glycemic index in chronic disease: a review. Augustin LS, Franceschi S, Jenkins DJ, Kendall CW, La Vecchia C. Eur J Clin Nutr. 2002 Nov;56(11):1049-71. Review. 14. Glycemic index, glycemic load, and chronic disease risk–a meta-analysis of observational studies. Barclay AW, Petocz P, McMillan-Price J, Flood VM, Prvan T, Mitchell P, Brand-Miller JC. Am J Clin Nutr. 2008 Mar;87(3):627-37. Review. 15. Glycemic Index Values takes from BloodIndex.com 16. Effects of pre-exercise ingestion of trehalose, galactose and glucose on subsequent metabolism and cycling performance. R.L.P.G. Jentjens. A.E. Jeukendrup. Eur J Appl Physiol (2003) 88: 459–465 17. What Are Sugar Alcohols? Comparisons and Blood Sugar Impact. Laura Dolson, About.com. Updated: April 13, 2009 18. Pre-exercise carbohydrate and fluid ingestion: influence of glycemic response on 10-km run treadmill running performance in the heat. Mitchell JB et al. J Sports Med Phys Res 40: 41-50 1989. 19. Carbohydrate ingestion can completely suppress endogenous glucose production during exercise. Asker E. Jeukendrup et al. Am J Physiol Endocrinol Metab 276: E672-E683, 1999 20. Determinants of post-exercise glycogen synthesis during short-term recovery. Jentjens R, Jeukendrup A. Sports Med. 2003;33(2):117-44. 21. Muscle glycogen synthesis after exercise: effect of time of carbohydrate ingestion. Ivy JL, Katz AL, Cutler CL, Sherman WM, Coyle EF. J Appl Physiol. 1988 Apr;64(4):1480-5. 22. Muscle glycogen synthesis before and after exercise. – Ivy JL – Sports Med – 01-JAN-1991; 11(1): 6-19 23. Muscle glycogen synthesis after exercise: effect of time of carbohydrate ingestion. Ivy JL, Katz AL, Cutler CL, Sherman WM, Coyle EF. J Appl Physiol. 1988 Apr;64(4):1480-5. 24. Dietary strategies to promote glycogen synthesis after exercise. Ivy JL. Can J Appl Physiol. 2001;26 Suppl:S236-45. 25. Determinants of post-exercise glycogen synthesis during short-term recovery. Jentjens R, Jeukendrup A. Sports Med. 2003;33(2):117-44. 26. Glycogen depletion and increased insulin sensitivity and responsiveness in muscle after exercise. Zorzano A, Balon TW, Goodman MN, Ruderman NB. Am J Physiol. 1986 Dec;251(6 Pt 1):E664-9. 27. Protein supplements and exercise. Wolfe RR. Am J Clin Nutr. 2000 Aug;72(2 Suppl):551S-7S. 28. Intracellular signalling pathways regulating the adaptation of skeletal muscle to exercise and nutritional changes. Matsakas A, Patel K. Histol Histopathol. 2009 Feb;24(2):209-22. 29. Recovery from a cycling time trial is enhanced with carbohydrate-protein supplementation vs. isoenergetic carbohydrate supplementation. Berardi JM, Noreen EE, Lemon PW. J Int Soc Sports Nutr. 2008 Dec 24;5:24. 30. Early postexercise muscle glycogen recovery is enhanced with a carbohydrate-protein supplement. Ivy JL, Goforth HW Jr, Damon BM, McCauley TR, Parsons EC, Price TB. J Appl Physiol. 2002 Oct;93(4):1337-44. 31. Nutrition strategies for the marathon : fuel for training and racing. Burke LM. Sports Med. 2007;37(4-5):344-7. 32. International Society of Sports Nutrition position stand: nutrient timing. Kerksick C, Harvey T, Stout J, Campbell B, Wilborn C, Kreider R, Kalman D, Ziegenfuss T, Lopez H, Landis J, Ivy JL, Antonio J. J Int Soc Sports Nutr. 2008 Oct 3;5:17. 33. What Are Sugar Alcohols? Comparisons and Blood Sugar Impact. Laura Dolson, About.com. April 13, 2009 34. Xylitol chewing gum and dental caries. Tanzer JM. Int Dent J. 1995 Feb;45(1 Suppl 1):65-76. Review. 35. New insights on trehalose: a multifunctional molecule. Elbein AD, Pan YT, Pastuszak I, Carroll D. Glycobiology. 2003 Apr;13(4):17R-27R. Epub 2003 Jan 22. 36. Effects of pre-exercise ingestion of trehalose, galactose and glucose on subsequent metabolism and cycling performance. Jentjens RL, Jeukendrup AE. Eur J Appl Physiol. 2003 Jan;88(4-5):459-65. Epub 2002 Nov 27. 37. Glucose polymer molecular weight does not affect exogenous carbohydrate oxidation. Rowlands DS. et al. Med Sci Sports Exerc. 37: 1510-16. 2005 38. The Influence of starch structure on Glycogen Resynthesis and Subsequent Cycling Performance. Jozsi A.C. et al. Int. J. Sports. Med. 17: 373-378. 1996 39. The Effects of Pre-Exercise Starch Ingestion on Endurance Performance. Goodpaster B.H. et al. Int. J. Sports Med. 17: 366-372. 1996. 40. Improved Gastric Emptying Rate in Humans of a Unique Glucose Polymer with Gel-forming Properties. Leiper J. B. Scan. J. Gastroenterol. 11: 1141-1149. 2000 41. Muscle glycogen resynthesis rate in humans after supplementation of drinks containing carbohydrates with low and high molecular masses. Piehl K. et al. Eur. J. Physiol. 81: 346-351. 2000 42. Setting The Record Straight on the Waxy Maize Craze. Will Brink. 02/24/2009. Muscular Development Magazine Online. 43. The effect of 7 to 8 months of vitamin/mineral supplementation on athletic performance. Telford RD, Catchpole EA, Deakin V, Hahn AG, Plank AW. Int J Sport Nutr. 1992 Jun;2(2):135-53. 44. Riboflavin requirements and exercise adaptation in older women. Winters LR, Yoon JS, Kalkwarf HJ, Davies JC, Berkowitz MG, Haas J, Roe DA. Am J Clin Nutr. 1992 Sep;56(3):526-32. 45. Riboflavin responsive multiple acyl-CoA dehydrogenase deficiency: functional evaluation of recovery after high dose vitamin supplementation. Peluchetti D, Antozzi C, Roi S, DiDonato S, Cornelio F. J Neurol Sci. 1991 Sep;105(1):93-8. 46. Vitamin supplementation and athletic performance. Williams MH. Int J Vitam Nutr Res Suppl. 1989;30:163-91. Review. 47. Effects of pantothenic acid supplementation on human exercise. Littoff D. et al. Med Sci Sports Exerc 1985 17(5- S) 287. 48. Athletic performance and vitamin D. Cannell JJ et al. Med Sci Sports Exerc 2009 Apr 3. [Epub] 49. Alpha-tocopherol supplementation prevents the exercise-induced reduction of serum paraoxonase 1/arylesterase activities in healthy individuals.Tsakiris S, Karikas GA, Parthimos T, Tsakiris T, Bakogiannis C, Schulpis KH. Eur J Clin Nutr. 2009 Feb;63(2):215-21. Epub 2007 Sep 19. 50. Testosterone levels in athletes at rest and exhaustion: effects of calcium supplementation. Cinar V, Baltaci AK, Mogulkoc R, Kilic M. Biol Trace Elem Res. 2009 Summer;129(1-3):65-9. Epub 2008 Dec 20. 51. Sodium phosphate loading improves laboratory cycling time-trial performance in trained cyclists. Folland JP, Stern R, Brickley G. J Sci Med Sport. 2008 Sep;11(5):464-8. Epub 2007 Jun 14. 52. Vitamin and mineral supplementation to athletes. Haymes EM. Int J Sport Nutr. 1991 Jun;1(2):146-69. 53. Acetyl-L-carnitine. Altern Med Rev. Dec;4(6) 438-41. 1999. 54. Carnitine metabolism during exercise. Brass EP, Hiatt WR. Life Sci. 1994;54(19):1383-93. 55. Acetyl-L-carnitine as a precursor of acetylcholine. White HL, Scates PW. Neurochem Res. 1990 Jun;15(6):597-601. 56. Acetyl-L-carnitine treatment stimulates oxygen consumption and biosynthetic function in perfused liver of young and old rats. Mollica MP, Iossa S, Soboll S, Liverini G. Cell Mol Life Sci. 2001 Mar;58(3):477-84. 57. Acetyl-l-carnitine inhibits TNF-alpha-induced insulin resistance via AMPK pathway in rat skeletal muscle cells. Zhang Z, Zhao M, Li Q, Zhao H, Wang J, Li Y. FEBS Lett. 2009 Jan 22;583(2):470-4. Epub 2008 Dec 31. 58. Acetyl-L-carnitine. Altern Med Rev. 1999 Dec;4(6):438-41. 59. A DIGE approach for the assessment of rat soleus muscle changes during unloading: effect of acetyl-L-carnitine supplementation. Moriggi M, Cassano P et al. Proteomics. 2008 Sep;8(17):3588-604. 60. Acetyl-L-carnitine supplementation differently influences nutrient partitioning, serum leptin concentration and skeletal muscle mitochondrial respiration in young and old rats. Iossa S, Mollica MP, Lionetti L, Crescenzo R, Botta M, Barletta A, Liverini G. J Nutr. 2002 Apr;132(4):636-42. 61. Acetyl-L-carnitine administration increases insulin-like growth factor 1 levels in asymptomatic HIV-1-infected subjects: correlation with its suppressive effect on lymphocyte apoptosis and ceramide generation. Di Marzio L, Moretti S, et al. Clin Immunol. 1999 Jul;92(1):103-10. 62. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue. Malaguarnera M, Gargante MP, Cristaldi E, Colonna V, Messano M, Koverech A, Neri S, Vacante M, Cammalleri L, Motta M. Arch Gerontol Geriatr. 2008 MarApr;46(2):181-90. Epub 2007 Jul 20 63. Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome. Vermeulen RC, Scholte HR. Psychosom Med. 2004 Mar-Apr;66(2):276-82. 64. Anticancer activities of adenine nucleotides in mice are mediated through expansion of erythrocyte ATP pools. Rapaport E, and Fontaine J: Proc. Natl. Acad. Sci. USA 1989; 86:1662-1666 65. ATP executive summary. Eliezer Rapaport, Ph.D. TSI Health Sciences (http://www.peakatp.com/research.php) 66. A randomized, double-blind, placebo controlled triphosphate in study of oral adenosine subacute low back pain. Bannwarth B, Allaert FA, Avouac B, Rossignol M, Rozenberg S, Valat JP. J Rheumatol. 2005;Jun;32(6):1114-1117 67. Effects of oral ATP supplementation on anaerobic power and muscular strength. Jordan AN, Jurca R. et al. Med Sci Sports Exerc. 2004 Jun;36(6):983-90. 68. Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine, on scopolamine-induced amnesia and brain acetylcholine. Lopez CM, Govoni S. et al. Pharmacol Biochem Behav. 1991 Aug;39(4):835-40. 69. Major mechanisms involved in the synaptic transmission of the neuromuscular apparatus. Rigoard S, Wager M, Buffenoir K, Bauche S, Giot JP, Maixent JM, Rigoard P. Neurochirurgie. 2009 Mar;55 Suppl 1:S22-33. Epub 2009 Feb 20. 70. Contributions of acetylcholine and nitric oxide to forearm blood flow at exercise onset and recovery. Shoemaker JK, Halliwill JR, Hughson RL, Joyner MJ. Am J Physiol. 1997 Nov;273(5 Pt 2):H2388-95. 71. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. Tim Ziefenfuss et al. JISSN 5:S1 15-16. 2008. 72. Alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, Meli M, Panzarasa R. Ann N Y Acad Sci. 1994 Jun 30;717:253-69. 73. Oxidation of leucine and alpha-ketoisocaproate to beta-hydroxy-beta-methylbutyrate in vivo.Van Koevering M, Nissen S. Am J Physiol. 1992 Jan;262(1 Pt 1):E27-31. 74. Nitrogen sparing by 2-ketoisocaproate in parenterally fed rats. Yagi M, Matthews DE, Walser M. Am J Physiol. 1990 Nov;259(5 Pt 1):E633-8. 75. Effects of alpha-ketoisocaproate and of leucine on nitrogen metabolism in postoperative patients. Sapir DG, Stewart PM. Et al. Lancet. 1983 May 7;1(8332):1010-4. 76. alpha-Ketoisocaproate is superior to leucine in sparing glucose utilization in humans. Buckspan R, Hoxworth B, Cersosimo E, Devlin J, Horton E, Abumrad N. Am J Physiol. 1986 Dec;251(6 Pt 1):E648-53. 77. The effects of short-term alpha-ketoisocaproic acid supplementation on exercise performance: a randomized controlled trial. Yarrow JF, Parr JJ, White LJ, Borsa PA, Stevens BR. J Int Soc Sports Nutr. 2007 Jul 13;4:2 78. Influence of alpha-ketoisocaproate on lamb growth, feed conversion, and carcass composition. Flakoll PJ, VandeHaar MJ, Kuhlman G, Nissen S. J Anim Sci. 1991 Apr;69(4):1461-7. 79. The effects of short-term alpha-ketoisocaproic acid supplementation on exercise performance: a randomized controlled trial. Yarrow JF, Parr JJ, White LJ, Borsa PA, Stevens BR. J Int Soc Sports Nutr. 2007 Jul 13;4:2. 80. Alpha-lipoic acid. Jane Higdon, Ph.D. Linus Pauling Institute. Micronutrient Research for Optimum Health. April 10, 2006. 81. Alpha-lipoic acid Monograph. Alternative Medicine Review 11(3) 232-237, 2005 82. Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle. Lee WJ, Song KH, Koh EH, Won JC, Kim HS, Park HS, Kim MS, Kim SW, Lee KU, Park JY. Biochem Biophys Res Commun. 2005 Jul 8;332(3):885-91. 83. Interactions of exercise training and alpha-lipoic acid on insulin signaling in skeletal muscle of obese Zucker rats. Saengsirisuwan V, Perez FR, Sloniger JA, Maier T, Henriksen EJ. Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E529-36. Epub 2004 Apr 6. 84. A-Lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy. Y Kishi et al. Diabetes 48:2045-51, 1999 85. Studies of energy-linked reactions. Net synthesis of adenosine triphosphate by isolated adenosine triphosphate synthase preparations: a role for lipoic acid and unsaturated fatty acids. Griffiths DE. Biochem J. 1976 Dec 15;160(3):809-12. 86. Interaction of alpha-lipoic acid enantiomers and homologues with the enzyme components of the mamilian pyruvate dehydrogenase complex. Loffelhardt S et al. Biochem Pharmacol 50:637-46, 1995 87. Mitochondrial ageing and the beneficial role of alpha-lipoic acid. Palaniappan AR, Dai A. Neurochem Res. 2007 Sep;32(9):1552-8. Epub 2007 May 3. 88. Enantioselective pharmacokinetics and bioavailability of different racemic alpha-lipoic acid formulations in healthy volunteers. Hermann R, Niebch G, Borbe HO, et al. Eur J Pharm Sci. 1996;4:167-174. 89. Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle. Streeper RS, Henriksen EJ, Jacob S, Hokama JY, Fogt DL, Tritschler HJ. Am J Physiol. 1997;273(1 Pt 1):E185-191 90. Improvement of insulin sensitivity in patients with type 2 diabetes mellitus after oral administration of alphalipoic acid. Kamenova P. Hormones (Athens). 2006 Oct-Dec;5(4):251-8. 91. Interactions of exercise training and lipoic acid on skeletal muscle glucose transport in obese Zucker rats. Saengsirisuwan V, Kinnick TR, Schmit MB, Henriksen EJ. J Appl Physiol. 2001 Jul;91(1):145-53. 92. Studies on aromatase inhibition with 4-androstene-3,6,17-trione: its 3 beta-reduction and time-dependent irreversible binding to aromatase with human placental microsomes. Numazawa M, Tsuji M, Mutsumi A. J Steroid Biochem 1997, 28:337-44. 93. Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback. Hayes F, Seminara S, Decruz S, Boepple P, Crowley W J Clin Endocrinob Metab 2000, 85:3027-35 94. Proof of the effect of testosterone on skeletal muscle. Bhasin S, Woodhouse L, Storer T J Endocrinol 2001, 170:27-38. Bhasin S, Woodhouse L, Storer T 95. Testosterone dose-response relationships in healthy young men. Bhasin S, Woodhouse L, Casaburi R at al. Am J Physiol Endocrinol Metab 2001, 281:E1172-81 96. Low-dose estrogen supplementation improves vascular function in hypogonadal men. Komesaroff PA, Fullerton M, Esler MD, Dart A, Jennings G, Sudhir K. Hypertension. 2001 Nov;38(5):1011-6. 97. Short-term aromatase inhibition: effects on gucose metabolism and serum leptin levels in young and elderly men. B Lapauw et al. Eur J Endocrinol 160(3): 397-402 (2009). 98. Effects of eight weeks of an alleged aromatase inhibiting nutritional supplement 6-OXO (androst-4-ene-3,6,17-trione) on serum hormone profiles and clinical safety markers in resistance-trained, eugonadal males. Rohle D, Wilborn C, Taylor L, Mulligan C, Kreider R, Willoughby D. J Int Soc Sports Nutr. 2007 Oct 19;4:13. 99. Contribution of meat fat to dietary arachidonic acid. Li D, Ng A, Mann NJ, Sinclair AJ. Lipids. 1998 Apr;33(4):437-40. 100. The Eicosanoids: Prostaglandins, thromboxanes, leukotrienes, & related compounds. E Smith, G FitzGerald. Chapter 18. Basic & Clinical Pharmacology. Bertram Katzung. (LANGE Basic Science). 2007. 101. Prenatal long-chain polyunsaturated fatty acid status: the importance of a balanced intake of docosahexaenoic acid and arachidonic acid. Hadders-Algra M. J Perinat Med. 2008;36(2):101-9. 102. Arachidonic acid metabolism in brain physiology and pathology: lessons from genetically altered mouse models. Bosetti F. J Neurochem. 2007 Aug;102(3):577-86. Epub 2007 Apr 2. Review. 103. Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology. Harizi H, Corcuff JB, Gualde N. Trends Mol Med. 2008 Oct;14(10):461-9. Epub 2008 Sep 4. 104. Arachidonic acid, prostaglandin E2 and F2 alpha influence rates of protein turnover in skeletal and cardiac muscle. Rodemann HP, Goldberg AL. J Biol Chem. 1982 Feb 25;257(4):1632-8. 105. Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.Trappe TA, White F, Lambert CP, Cesar D, Hellerstein M, Evans W. Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E551-6. 106. Protein synthesis in isolated forelimb muscles. The possible role of metabolites of arachidonic acid in the response to intermittent stretching. Smith, Palmer et al. Biochem J. 1983 214,153-61 107. Prostaglandin F2 alpha stimulates proliferation of clonal osteoblastic MC3T3-E1 cells by up-regulation of insulin-like growth factor I receptors. Hakeda Y, Harada S, Matsumoto T, Tezuka K, Higashino K, Kodama H, Hashimoto-Goto T, Ogata E, Kumegawa M. J Biol Chem. 1991 Nov 5;266(31):21044-50. 108. Dietary effects of arachidonate-rich fungal oil and fish oil on murine hepatic and hippocampal gene expression. Berger A, Mutch DM, German JB, Roberts MA. Lipids Health Dis. 2002 Oct 21;1:2. 109. The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. Borkman M, Storlien LH, Pan DA, Jenkins AB, Chisholm DJ, Campbell LV. N Engl J Med. 1993 Jan 28;328(4):238-44. 110. Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion. Mendias CL, Tatsumi R, Allen RE. Muscle Nerve. 2004 Oct;30(4):497-500. 111. Prostaglandins are involved in acetylcholine- and 5-hydroxytryptamine-induced, nitric oxide-mediated vasodilatation in human forearm. Kamper AM, Paul LC, Blauw GJ. J Cardiovasc Pharmacol. 2002 Dec;40(6):922-9. 112. Relative incorporation of linoleic and arachidonic acid in phospholipids and triglycerides of different rat tissues. Catala A, Brenner RR. Lipids. 1967 Mar;2(2):114-21. 113. Stretch-induced prostaglandins and protein turnover in cultured skeletal muscle. Vandenburgh HH, Hatfaludy S, Sohar I, Shansky J. Am J Physiol. 1990 Aug;259(2 Pt 1):C232-40. 114. Prostaglandins and thromboxanes. Falardeau P, Martineau A, Gagnon D. Sem Hop. 1984 Apr 12;60(16):1117-36. 115. Effects of physical exercise on phospholipid fatty acid composition in skeletal muscle. Andersson A, Sjödin A, Olsson R, Vessby B. Am J Physiol. 1998 Mar;274(3 Pt 1):E432-8. 116. Effects of exercise on parameters of blood coagulation, platelet function and the prostaglandin system. H Sinzinger, I Vergolini. Sports Med 6: 238-45 (1988) 117. Effects of arachidonate-enriched triacylglycerol supplementation on serum fatty acids and platelet aggregation in healthy male subjects with a fish diet. Kusumoto A, Ishikura Y, Kawashima H, Kiso Y, Takai S, Miyazaki M. Br J Nutr. 2007 Sep;98(3):626-35. Epub 2007 Apr 20. 118. Measurement of the incorporation of orally administered arachidonic acid into tissue lipids. R Kulmacz. Lipids 21, 21-25 (1986). 119. Effects of arachidonate-enriched triacylglycerol supplementation on serum fatty acids and platelet aggregation in healthy male subjects with a fish diet. Aki Kusumoto et al. British Journal of Nutrition (2007), 98:626-635. 120. Effects of arachidonic acid supplementation on training adaptations in resistance-trained males. Roberts MD, Iosia M, Kerksick CM, Taylor LW, Campbell B, Wilborn CD, Harvey T, Cooke M, Rasmussen C, Greenwood M, Wilson R, Jitomir J, Willoughby D, Kreider RB. J Int Soc Sports Nutr. 2007 Nov 28;4:21. 121. The Proving Grounds: Arachidonic Acid. W. Llewellyn. Body of Science. Summer 2003. Page 15-19 122. Changes in whole blood and clinical safety markers over 50 days of concomitant arachidonic acid supplementation and resistance training. Wilborn, C, M Roberts, C Kerksick, M Iosia, L Taylor, B Campbell, T Harvey, R Wilson, M. Greenwood, D Willoughby and R Kreider. Proceedings of the International Society of Sports Nutrition (ISSN) Conference June 15-17, 2006. 123. The effect of dietary arachidonic acid on plasma lipoprotein distributions, apoproteins, blood lipid levels, and tissue fatty acid composition in humans. Nelson GJ, Schmidt PC, Bartolini G, Kelley DS, Phinney SD, Kyle D, Silbermann S, Schaefer EJ. Lipids. 1997 Apr;32(4):427-33. 124. Arachidonic acid supplementation enhances synthesis of eicosanoids without suppressing immune functions in young healthy men. Kelley DS, Taylor PC, Nelson GJ, Mackey BE. Lipids. 1998 Feb;33(2):125-30. 125. The effect of dietary arachidonic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Nelson GJ, Schmidt PC, Bartolini G, Kelley DS, Kyle D. Lipids. 1997 Apr;32(4):421-5. 126. The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. Borkman M, Storlien LH, Pan DA, Jenkins AB, Chisholm DJ, Campbell LV.N Engl J Med. 1993 Jan 28;328(4):238-44. 127. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Harris WS, Mozaffarian D, Rimm E, Kris-Etherton P, Rudel LL, Appel LJ, Engler MM, Engler MB, Sacks F. Circulation. 2009 Feb 17;119(6):902-7. Epub 2009 Jan 26. 128. The effect of dietary arachidonic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Nelson GJ, Schmidt PC, Bartolini G, Kelley DS, Kyle D. Lipids. 1997 Apr;32(4):421-5. 129. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Harris WS, Mozaffarian D, Rimm E, Kris-Etherton P, Rudel LL, Appel LJ, Engler MM, Engler MB, Sacks F. Circulation. 2009 Feb 17;119(6):902-7. Epub 2009 Jan 26. 130. Changes in whole blood and clinical safety markers over 50 days of concomitant arachidonic acid supplementation and resistance training. Wilborn, C, M Roberts, C Kerksick, M Iosia, L Taylor, B Campbell, T Harvey, R Wilson, M. Greenwood, D Willoughby and R Kreider. Proceedings of the International Society of Sports Nutrition (ISSN) Conference June 15-17, 2006. 131. Effects of dietary supplementation with arachidonic acid on platelet and renal function in patients with cirrhosis. Pantaleo, P, Marra, F, Vizzutti, F, Spadoni, S, Ciabattoni, G, Galli, C, Villa, GL, Gentilini, P & Laffi, G (2004) Clin Sci 106, 27–34. 132. Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. Ferrucci L et al. J Clin Endocrinol Metab 91: 439-46. 2006. 133. Antithetic relationship of dietary arachidonic acid and eicosapentaenoic acid on eicosanoid production in vivo. Li B, Birdwell C, Whelan J. J Lipid Res. 1994 Oct;35(10):1869-77. 134. Arginine: Biochemistry, physiology, and therapeutic implications. A Barbul. JPEN 10(2):227-238 (1986) 135. The ergogenic potential of arginine. B. Campbell, P. La Bounty, M. Roberts. JISSN 1(2):35-38 (2004) 136. Oral arginine attenuates the growth hormone response to resistance exercise. S.R. Collier et al. J Appl Physiol 101: 848-852 (2006) 137. Growth hormone responses to varying doses of oral arginine. Collier SR, Casey DP, Kanaley JA. Growth Horm IGF Res. 2005 Apr;15(2):136-9. Epub 2005 Jan 26. 138. Study on the effect of oral administration of l-arginine on muscular performance in healthy volunteers: an isokinetic study. Santos RS et al. Isokinet Exerc Sci 2002; 10:153-8. 139. Effects of arginine and ornithine on strength, lean body mass and urinary hydroxyproline in adult males. Elam RP, Hardin DH, Sutton RA, Hagen L. J Sports Med Phys Fitness. 1989 Mar;29(1):52-6. 140. Influence of chronic supplementation of arginine aspartate in endurance athletes on performance and substrate metabolism – a randomized, double-blind, placebo-controlled study. Abel T, Knechtle B, Perret C, Eser P, von Arx P, Knecht H. Int J Sports Med. 2005 Jun;26(5):344-9. 141. No effect of short-term arginine supplementation on nitric oxide production, metabolism and performance in intermittent exercise in athletes. Liu TH, Wu CL, Chiang CW, Lo YW, Tseng HF, Chang CK. J Nutr Biochem. 2009 Jun;20(6):462-8. Epub 2008 Aug 15. 142. Hemodynamic and vascular response to resistance exercise with L-arginine. Fahs CA, Heffernan KS, Fernhall B. Med Sci Sports Exerc. 2009 Apr;41(4):773-9. 143. Potential ergogenic effects of arginine and creatine supplementation. D. Paddon-Jones et al. J. Nutr. 134: 2888S2894S (2004) 144. The ergogenic potential of arginine. B. Campbell, P. La Bounty, M. Roberts. JISSN 1(2):35-38 (2004) 145. The effect of sodium alpha-ketoglutarate on the physical load endurance of rats with different resistances to hypoxia. Kurhaliuk NM. Fiziol Zh. 2000;46(4):88-95. 146. The use of alpha-ketoglutarate salts in clinical nutrition and metabolic care. Cynober LA. Curr Opin Clin Nutr Metab Care. 1999 Jan;2(1):33-7. 147. Pharmacokinetics, safety, and effects on exercise performance of L-arginine alpha-ketoglutarate in trained adult men. Campbell B, Roberts M, Kerksick C, Wilborn C, Marcello B, Taylor L, Nassar E, Leutholtz B, Bowden R, Rasmussen C, Greenwood M, Kreider R. Nutrition. 2006 Sep;22(9):872-81. 148. Carnosine protects against the inactivation of esterase induced by glycation and a steroid. Yan Hong; Harding John J. Biochimica et biophysica acta 2005;1741(1-2):120-6. 149. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. C.A. Hill et al. Amino Acids, 2007 Feb;32(2):225-33 150. b-Alanine and the Hormonal Response to Exercise J. Hoffman, N. A. Ratamess et al. Int J Sports Med 2008; 29: 952-958 151. Short-duration beta-alanine supplementation increases training volume and reduces subjective feelings of fatigue in college football players. Hoffman JR, Ratamess NA. et al. Nutr Res. 2008 Jan;28(1):31-5. 152. Effects of beta-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial. Smith AE, Walter AA et al. J Int Soc Sports Nutr. 2009 Feb 11;6:5. 153. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus ateralis. R.C. Harris et al. Amino Acids 30: 279-89 (2006) 154. Betaine in human nutrition. Stuart AS Craig. Am J Clin Nutr 2004; 80:539-49. 155. Influence of betaine consumption on strenuous running and sprinting in a hot environment. Armstrong LE et al. J Strength Cond Res. 2008 May; 22(3):851-60. 156. A further investigation of the role of betaine in transmethylation reactions in vivo. Du Vigneaud V. et al. J Biol Chem 1946, 165:639-48. 157. Effect of betaine supplementation on power performance and fatigue. J Hoffman, N Ratamess et al. J Int Soc Sport Nutr 2009, 6:7 158. The effects of betaine supplementation on strength and power performance. Maresh CM et al. Med Sci Sports Exerc 2008, 39:S101. 159. Influence of betaine consumption on strenuous running and sprinting in a hot environment. Armstrong LE et al. J Strength Cond Res. 2008 May; 22(3):851-60. 160. The total branched-chain amino acid requirement in young healthy adult men determined by indicator amino acid oxidation by use of L-[1-13C]phenylalanine. Riazi R, Wykes LJ, Ball RO, Pencharz PB. J Nutr. 2003 May;133(5):1383-9. 161. Dietary protein impact on glycemic control during weight loss. Layman DK, Baum JI. J Nutr. 2004 Apr;134(4):968S-73S. 162. Nutraceutical effects of branched-chain amino acids on skeletal muscle. Shimomura Y, Yamamoto Y, Bajotto G, Sato J, Murakami T, Shimomura N, Kobayashi H, Mawatari K. J Nutr. 2006 Feb;136(2):529S-532S. 163. Plasma branched-chain amino acid levels and muscle energy metabolism in patients with chronic obstructive pulmonary disease. Kutsuzawa T, Shioya S, Kurita D, Haida M. Clin Nutr. 2009 Apr;28(2):203-8. Epub 2009 Feb 27 164. Branched-chain amino acids and immunity. Calder PC. J Nutr. 2006 Jan;136(1 Suppl):288S-93S. Review. 165. A role for branched-chain amino acids in reducing central fatigue. Blomstrand E. J Nutr. 2006 Feb;136(2):544S547S. 166. Nutraceutical effects of branched-chain amino acids on skeletal muscle. Shimomura Y, Yamamoto Y, Bajotto G, Sato J, Murakami T, Shimomura N, Kobayashi H, Mawatari K. J Nutr. 2006 Feb;136(2):529S-532S. 167. Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise. Shimomura Y, Murakami T, Nakai N, Nagasaki M, Harris RA. J Nutr. 2004 Jun;134(6 Suppl):1583S-1587S. 168. Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis. Drummond MJ, Rasmussen BB. Curr Opin Clin Nutr Metab Care. 2008 May;11(3):222-6. 169. The effects of BCAA and leucine supplementation and lower-body resistance exercise on the ERK 1/2 MAPK pathway signal transduction. Bill Campbell et al. JISSN 2008, 5 (Suppl 1): P19 170. Plasma lactate, GH and GH-binding protein levels in exercise following BCAA supplementation in athletes. De Palo EF, Gatti R, Cappellin E, Schiraldi C, De Palo CB, Spinella P. Amino Acids. 2001;20(1):1-11. 171. Branched-chain amino acids augments ammonia metabolism while attenuating protein breakdown during exercise. MacLean D et al. Am. J. Physiol. 267: E1010-22. 172. Branched-chain amino acids and arginine supplementation attenuates skeletal muscle proteolysis induced by moderate exercise in young individuals. Matsumoto K, Mizuno M, Mizuno T, Dilling-Hansen B, Lahoz A, Bertelsen V, Münster H, Jordening H, Hamada K, Doi T. Int J Sports Med. 2007 Jun;28(6):531-8. Epub 2007 May 11. 173. Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise. Shimomura Y, Murakami T, Nakai N, Nagasaki M, Harris RA. J Nutr. 2004 Jun;134(6 Suppl):1583S-1587S. Review. 174. BCAA intake affects protein metabolism in muscle after but not during exercise in humans. E Blomstrand et al. Am J Physiol Endocrinol Metab 281: E365-74, 2001. 175. Effects of branched-chain amino acid supplementation on serum creatine kinase and lactate dehydrogenase after prolonged exercise. Coombes JS, McNaughton LR. J Sports Med Phys Fitness. 2000 Sep;40(3):240-6. 176. The branched-chain amino acids. Chiarla C, Giovannini I, Boldrini G, Castagneto M. Minerva Gastroenterol Dietol. 1997 Dec;43(4):189-96. 177. Effect of chronic supplementation with branched-chain amino acids on the performance and hepatic and muscle glycogen content in trained rats. de Araujo JA Jr, Falavigna G, Rogero MM, Pires IS, Pedrosa RG, Castro IA, Donato J Jr, Tirapegui J. Life Sci. 2006 Aug 29;79(14):1343-8. Epub 2006 Apr 22. 178. Plasma lactate, GH and GH-binding protein levels in exercise following BCAA supplementation in athletes. De Palo EF, Gatti R, Cappellin E, Schiraldi C, De Palo CB, Spinella P. Amino Acids. 2001;20(1):1-11. 179. Administration of branched-chain amino acids during sustained exercise–effects on performance and on plasma concentration of some amino acids. Blomstrand E, Hassmén P, Ekblom B, Newsholme EA. Eur J Appl Physiol Occup Physiol. 1991;63(2):83-8. 180. Branched-chain amino acids prolong exercise during heat stress in men and women. Mittleman KD, Ricci MR, Bailey SP. Med Sci Sports Exerc. 1998 Jan;30(1):83-91. 181. Effect of acute and chronic branched-chain amino acids on energy metabolism and muscle performance. De Lorenzo A et al. Diabetes Nutr Metab. 2003 Oct-Dec;16(5-6):291-7. 182. Branched-chain amino acid supplementation does not enhance athletic performance but affects muscle recovery and the immune system. Negro M, Giardina S, Marzani B, Marzatico F. J Sports Med Phys Fitness. 2008 Sep;48(3):347-51. Review 183. Branched-chain amino acid supplementation and human performance when hypohydrated in the heat. Cheuvront SN, Carter R 3rd, Kolka MA, Lieberman HR, Kellogg MD, Sawka MN. J Appl Physiol. 2004 Oct;97(4):1275-82. 184. Effects of branched-chain amino acids and carbohydrate on fatigue during intermittent, high-intensity running. Davis JM, Welsh RS, De Volve KL, Alderson NA. Int J Sports Med. 1999 Jul;20(5):309-14. 185. Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects. Rene´ Koopman et al. Am J Physiol Endocrinol Metab 288: E645–E653, 2005. 186. Determination of the effects of caffeine and carbamazepine on striatal dopamine release by in vivo microdialysis. Okada M, Kiryu K, Kawata Y, Mizuno K, Wada K, Tasaki H, Kaneko S. Eur J Pharmacol. 1997 Feb 26;321(2):181-8. 187. Studies on the mechanism of caffeine action in alveolar macrophages: caffeine elevates cyclic adenosine monophosphate level and prostaglandin synthesis. M.Jafari, A.Rabbani Metabolism, Volume 53, Issue 6, Pages 687- 692 188. Requirement of intact adenosine A1 receptors for the diuretic and natriuretic action of the methylxanthines theophylline and caffeine. Rieg T, Steigele H, Schnermann J, Richter K, Osswald H, Vallon V. J Pharmacol Exp Ther. 2005 Apr;313(1):403-9. Epub 2004 Dec 8. 189. Ergogenic effects of low doses of caffeine on cycling performance. Jenkins NT, Trilk JL, Singhal A, O’Connor PJ, Cureton KJ. Int J Sport Nutr Exerc Metab. 2008 Jun;18(3):328-42. 190. The effect of caffeine ingestion on 8 km run performance in a field setting. Bridge CA, Jones MA. J Sports Sci. 2006 Apr;24(4):433-9. 191. Benefits of caffeine ingestion on sprint performance in trained and untrained swimmers. Collomp K, Ahmaidi S, Chatard JC, Audran M, Préfaut C. Eur J Appl Physiol Occup Physiol. 1992;64(4):377-80. 192. Caffeine and sports performance. L Burke. Appl. Physiol. Nutr. Metab. 33: 1319-34 (2008) 193. Metabolic, catecholamine, and exercise performance responses to various doses of caffeine. Graham T.E. et al. J Appl. Physiol, 78: 867-74 (1995) 194. Carnitine and sports medicine: use or abuse? Brass EP. Ann NY Acad Sci 2004;1033:67-78 195. Carnitine. The science behind a conditionally essential nutrient. Proceedings of a conference. March 25-26, 2004. Bethesda, Maryland, USA. Ann N Y Acad Sci. 2004 Nov;1033:ix-xi; 1-197. 196. Carnitine function and requirements during the life cycle. Rebouche, C.J. et al. 1992. FASEB J. 6: 3379–3386. 197. Exercise physiology in health and disease. Wasserman K, Whipp BJ. Am Rev Resp Dis 112:219–249, 1975. 198. Antioxidant and antiradical activities of L-carnitine. Gülçin I. Life Sci. 2006 Jan 18;78(8):803-11. Epub 2005 Oct 25. 199. Correlation of serum L-carnitine and dehydro-epiandrosterone sulphate levels with age and sex in healthy adults. Chiu KM, Schmidt MJ, Havighurst TC, Shug AL, Daynes RA, Keller ET, Gravenstein S. Age Ageing. 1999 Mar;28(2):211-6. 200. Efficacy of levo carnitine and alpha lipoic acid in ameliorating the decline in mitochondrial enzymes during aging. Savitha S, Sivarajan K, Haripriya D, Kokilavani V, Panneerselvam C. Clin Nutr. 2005 Oct;24(5):794-800. 201. Carnitine. Office of Dietary Supplements. National Institutes of Health. 6/15/2005. 202. Comparison of the Effects of L-Carnitine and Acetyl-L-Carnitine on Carnitine Levels, Ambulatory Activity, and Oxidative Stress Biomarkers in the Brain of Old Rats. Jiankang Liu. Ann. N.Y. Acad. Sci. 1033: 117–131 (2004) 203. The Role of Carnitine and Carnitine Supplementation During Exercise in Man and in Individuals with Special Needs. Eric P. Brass, MD, PhD and William R. Hiatt, MD. Journal of the American College of Nutrition, Vol. 17, No. 3, 207–215 (1998) 204. Studies concerning chronic and acute effects of L-carnitine on some biological parameters in elite athletes. Dragan GI, Vasiliu A, Georgescu E, Dumas I. Physiologie. 1987 Jan-Mar;24(1):23-8. 205. Decrease in respiratory quotient during exercise following L-carnitine supplementation. Gorostiaga EM, Maurer CA, Eclache JP. Int J Sports Med. 1989 Jun;10(3):169-74. 206. Influence of L-carnitine administration on maximal physical exercise. Vecchiet L, Di Lisa F, Pieralisi G, Ripari P, Menabò R, Giamberardino MA, Siliprandi N. Eur J Appl Physiol Occup Physiol. 1990;61(5-6):486-90. 207. Effects of L-carnitine loading on the aerobic and anaerobic performance of endurance athletes. Marconi C, Sassi G, Carpinelli A, Cerretelli P. Eur J Appl Physiol Occup Physiol. 1985;54(2):131-5. 208. Effects of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: a double-blind crossover field study. Colombani P, Wenk C. et al. Eur J Appl Physiol Occup Physiol. 1996;73(5):434-9. 209. Effect of L-carnitine supplementation on muscle and blood carnitine content and lactate accumulation during high-intensity sprint cycling. Barnett C, Costill DL, Vukovich MD et al. Int J Sport Nutr. 1994 Sep;4(3):280-8. 210. Carnitine supplementation: effect on muscle carnitine and glycogen content during exercise. Vukovich MD, Costill DL, Fink WJ. Med Sci Sports Exerc. 1994 Sep;26(9):1122-9. 211. The effects of L-carnitine supplementation on performance during interval swimming. Trappe SW, Costill DL, Goodpaster B, Vukovich MD, Fink WJ. Int J Sports Med. 1994 May;15(4):181-5. 212. Supplemental carnitine and exercise. E Brass. Am J Clin Nutr 2000; 72(suppl):618S-23S. 213. L-Carnitine supplementation combined with aerobic training does not promote weight loss in moderately obese women. Villani RG, Gannon J, Self M, Rich PA. Int J Sport Nutr Exerc Metab. 2000 Jun;10(2):199-207. 214. Analgesic, anti-inflammatory and venotonic effects of Cissus quadrangularis Linn. Panthong A, Supraditaporn W. et al. J Ethnopharmacol. 2007 Mar 21;110(2):264-70. Epub 2006 Sep 26. 215. Gastroprotective action of Cissus quadrangularis extract against NSAID induced gastric ulcer: role of proinflammatory cytokines and oxidative damage. Jainu M, Devi CS. Chem Biol Interact. 2006 Jul 10;161(3):262-70. Epub 2006 May 1. 216. Antioxidant and antimicrobial activity of Cissus quadrangularis L. Chidambara Murthy KN, Vanitha A, Mahadeva Swamy M, Ravishankar GA. J Med Food. 2003 Summer;6(2):99-105. 217. Gastroprotective effect of Cissus sicyoides (Vitaceae): involvement of microcirculation, endogenous sulfhydryls and nitric oxide. de Paula Ferreira M, Nishijima CM, Seito LN, Dokkedal AL, Lopes-Ferreira M, Di Stasi LC, Vilegas W, Hiruma-Lima CA. J Ethnopharmacol. 2008 Apr 17;117(1):170-4. Epub 2008 Jan 19 218. Studies on cissus quadrangularis linn. I. Acetylcholine like action of the total extract. Das PK, Sanyal AK. Indian J Med Res. 1964 Jan;52:63-7. 219. Inhibitory effects of Cissus quadrangularis L. derived components on lipase, amylase, and alpha-glucosidase activity in-vitro. S. Hollinshead et al. Natl Product Communications 2007, 2:817-22 220. Effect of cissus quadrangularis on the healing of cortisone treated fractures. Prasad GC et al. Indian J Med Res. 1963 Jul;51:667-76 221. The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. Oben JE, Enyegue DM, Fomekong GI, Soukontoua YB, Agbor GA. Lipids Health Dis. 2007 Feb 4;6:4. 222. Total-body skeletal muscle mass: evaluation of 24-h urinary creatinine excretion by computerized axial tomography. Wang ZM, Gallagher D, Nelson ME, Matthews DE, Heymsfield SB. Am J Clin Nutr. 1996 Jun;63(6):863-9. 223. The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a doubleblind placebo-controlled study. Oben JE, Ngondi JL, Momo CN, Agbor GA, Sobgui CS. Lipids Health Dis. 2008 Mar 31;7:12. 224. Watermelon consumption increases plasma arginine concentrations in adults. Collins, J. K.; Wu, G.; PerkinsVeazie, P.; Spears, K.; Claypool, P. L.; Baker, R. A.; Clevidence, B. A. Journal: Nutrition. 2007 Mar;23 (3):261-6. 225. Controlled double-blind clinical study against stimol placebo in the treatment of asthenia. Creff AF et al. Gazette Medicale de France. 1982;89:1926-9. 226. Activity of citrulline malate on acid-base balance and blood ammonia and amino acid levels. Study in the animal and in man. Callis A, Magnan de Bornier B, Serrano JJ, Bellet H, Saumade R. Arzneimittelforschung. 1991 Jun;41(6):660-3. 227. Influence of an anti-asthenia agent, citrulline malate, on serum lactate and ammonia kinetics during a maximum exercise test in sedentary subjects. Vanuxem D et al. Seminaire des Hopitaux de Paris. 1990;66:477-81. 228. Citrulline/malate promotes aerobic energy production in human exercising muscle. Bendahan D, Mattei JP, Ghattas B, Confort-Gouny S, Le Guern ME, Cozzone PJ. Br J Sports Med. 2002 Aug;36(4):282-9. 229. Pharmacoclinical approach of citrulline malate activity: analysis of blood lactate during a standardized exercise. Fornaris E et al. Gazette Medicale de France. 1984;91:1-3 230. Influence of an anti-asthenia agent, citrulline malate, on serum lactate and ammonia kinetics during a maximum exercise test in sedentary subjects. Vanuxem D et al. Seminaire des Hopitaux de Paris. 1990;66:477-81. 231. Pharmacological studies on coleonol, a hypotensive diterpene from Coleus forskohlii. Dubey MP, Srimal RC, Nityanand S et al. J Ethnopharmacol. 3:1-13 2006. 232. Forskolin versus sodium cromoglycate for prevention of asthma attacks: a single-blinded clinical trial. González Sánchez R et al. Int Med Res. 2006 Mar-Apr;34(2):200-7. 233. The effect of forskolin on blood flow, platelet metabolism, aggregation and ATP release. Christenson JT, Thulesius O, Nazzal MM. Vasa. 1995;24(1):56-61. 234. Effects of forskolin on canine congestive heart failure. Sonoki H, Uchida Y, Masuo M, Tomaru T, Katoh A, Sugimoto T. Nippon Yakurigaku Zasshi. 1986 Nov;88(5):389-94. 235. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Godard MP, Johnson BA, Richmond SR. Obes Res. 2005 Aug;13(8):1335-43. 236. Forskolin lowers intraocular pressure in rabbits, monkeys, and man. Caprioli J, Sears M. Lancet. 1983 Apr 30;1(8331):958-60. 237. Forskolin, adenylate cyclase, and cell physiology: an overview. Daly JW. Adv Cyclic Nucleotide Protein Phosphorylation Res. 1984;17:81-9. 238. Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action? Laurenza A, Sutkowski EM, Seamon KB. Trends Pharmacol Sci. 1989 Nov;10(11):442-7. 239. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Godard MP, Johnson BA, Richmond SR. Obes Res. 2005 Aug;13(8):1335-43. 240. Factors affecting conjugated linoleic acid content in milk and meat. Dhiman TR, Nam SH, Ure AL. Crit Rev Food Sci Nutr. 2005;45(6):463-82. Review. 241. A ‘good’trans fat? Keith-Thomas Ayoob. ABC News. April 24, 2007. 242. Emerging Health Benefits Of CLA (Conjugated Linoleic Acid). National Dairy Council http://www.nationaldairycouncil.org/NationalDairyCouncil/Health/Digest/dcd71-4Page1.htm 243. The potential benefits of creatine and conjugated linoleic acid as adjuncts to resistance training in older adults. M. Tarnopolsky, A. Safdar. Appl. Physiol. Nutr. Metab. 33: 213-27 (2008). 244. Moderate doses of conjugated linoleic acid isomers mix contribute to lowering body fat content maintaining insulin sensitivity and a noninflammatory pattern in adipose tissue in mice. Parra P, Serra F, Palou A. J Nutr Biochem. 2009 Feb 4. [Epub ahead of print] 245. Conjugated linoleic acid prevents growth attenuation induced by corticosteroid administration and increases bone mineral content in young rats.Roy BD, Bourgeois J, Rodriguez C, Payne E, Young K, Shaughnessy SG, Tarnopolosky MA. Appl Physiol Nutr Metab. 2008 Dec;33(6):1096-104. 246. Increased energy metabolism and suppressed body fat accumulation in mice by a low concentration of conjugated linoleic acid. Ohnuki K, Haramizu S, Ishihara K, Fushiki T. Biosci Biotechnol Biochem. 2001 Oct;65(10):2200- 4. 247. Effect of conjugated linoleic acid isomers on insulin resistance and mRNA levels of genes regulating energy metabolism in high-fat-fed rats. Choi JS, Jung MH, Park HS, Song J. Nutrition. 2004 Nov-Dec;20(11-12):1008-17. 248. Conjugated linoleic acid supplementation modified the body composition and serum leptin levels in weaning rats. Prais Botelho A, Santos-Zago LF, Costa de Oliveira A. Arch Latinoam Nutr. 2008 Jun;58(2):156-63. 249. Conjugated linoleic acid (CLA) and obesity. Silveira MB, Carraro R, Monereo S, Tébar J. Public Health Nutr. 2007 Oct;10(10A):1181-6. Review. 250. Isomer-specific effects of conjugated linoleic acid on gene expression in RAW 264.7. Lee Y, Thompson JT, de Lera AR, Vanden Heuvel JP. J Nutr Biochem. 2008 Nov 5. [Epub ahead of print] 251. Conjugated linoleic acid isomers: differences in metabolism and biological effects. Churruca I, Fernández-Quintela A, Portillo MP. Biofactors. 2009 Jan-Feb;35(1):105-11. Review. 252. Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J mice. Halade GV, Rahman MM, Fernandes G. J Nutr Biochem. 2009 May 6. [Epub ahead of print] 253. The effects of conjugated linoleic acid supplementation during resistance training. Pinkoski C, Chilibeck PD, Candow DG, Esliger D, Ewaschuk JB, Facci M, Farthing JP, Zello GA. Med Sci Sports Exerc. 2006 Feb;38(2):339- 48. 254. Effects of conjugated linoleic acid supplementation during resistance training on body composition, bone density, strength, and selected hematological markers. Kreider RB, Ferreira MP, Greenwood M, Wilson M, Almada AL. J Strength Cond Res. 2002 Aug;16(3):325-34. 255. Conjugated linoleic acid supplementation for twelve weeks increases lean body mass in obese humans. Steck SE, Chalecki AM, Miller P. J Nutr. 2007 May;137(5):1188-93. 256. Creatine: biosynthesis, regulation, and function. Walker J. Adv Enzym 50:117-242 (1979) 257. Creatine supplementation enhances anaerobic ATP synthesis during a single 10 sec maximal handgrip exercise. Kurosawa Y, Hamaoka T, Katsumura T, Kuwamori M, Kimura N, Sako T, Chance B. Mol Cell Biochem. 2003 Feb;244(1-2):105-12. 258. Creatine: biosynthesis, regulation, and function. Walker J. Adv Enzym 50:117-242 (1979) 259. Potential ergogenic effects of arginine and creatine supplementation. D Paddon-Jones et al. J Nutr 134:2888S2894S, 2004. 260. Creatine supplementation during resistance training in college football athletes. Bemben MG, Bemben DA, Loftiss DD, Knehans AW. Med Sci Sports Exerc. 2001 Oct;33(10):1667-73. 261. Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis. Parise G, Mihic S, MacLennan D, Yarasheski KE, Tarnopolsky MA. J Appl Physiol. 2001 Sep;91(3):1041-7. 262. Effect of creatine supplementation and resistance-exercise training on muscle insulin-like growth factor in young adults. Burke DG, Candow DG, Chilibeck PD, MacNeil LG, Roy BD, Tarnopolsky MA, Ziegenfuss T. Int J Sport Nutr Exerc Metab. 2008 Aug;18(4):389-98. 263. Increased IGF mRNA in human skeletal muscle after creatine supplementation. Deldicque L, Louis M, Theisen D, Nielens H, Dehoux M, Thissen JP, Rennie MJ, Francaux M. Med Sci Sports Exerc. 2005 May;37(5):731-6. 264. Effects of oral creatine and resistance training on myogenic regulatory factor expression.Willoughby DS, Rosene JM. Med Sci Sports Exerc. 2003 Jun;35(6):923-9. 265. Dietary creatine monohydrate supplementation increases satellite cell mitotic activity during compensatory hypertrophy. Dangott B, Schultz E, Mozdziak PE. Int J Sports Med. 2000 Jan;21(1):13-6. 266. Clinical pharmacology of the dietary supplement creatine monohydrate. Persky AM, Brazeau GA. Pharmacol Rev. 2001 Jun;53(2):161-76. 267. Creatine in sports. Kreider RB. Essentials of Sport Nutrition & Supplements. Humana Oress. Totowa, NJ. 2007. 268. Creatine supplementation: a comparison of loading and maintenance protocols on creatine uptake by human skeletal muscle. Preen D, Dawson B, Goodman C, Beilby J, Ching S. Int J Sport Nutr Exerc Metab. 2003 Mar;13(1):97-111. 269. Muscle creatine loading in men. Hultman E. et al. J Appl Physiol 81:232-37. (1996) 270. Kinetics of creatine ingestion as a food ingredient. Deldicque L et al. Eur J Appl Physiol 2008, 102(2): 133-43. 271. International Society of Sports Nutrition position stand: creatine supplementation and exercise. Buford TW, Kreider RB, Stout JR, Greenwood M, Campbell B, Spano M, Ziegenfuss T, Lopez H, Landis J, Antonio J. J Int Soc Sports Nutr. 2007 Aug 30;4:6. 272. Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. Volek JS, Duncan ND, Mazzetti SA, Staron RS, Putukian M, Gómez AL, Pearson DR, Fink WJ, Kraemer WJ. Med Sci Sports Exerc. 1999 Aug;31(8):1147-56. 273. Effect of in-season creatine supplementation on body composition and performance in rugby union football players. Chilibeck PD, Magnus C, Anderson M. Appl Physiol Nutr Metab. 2007 Dec;32(6):1052-7. 274. The effects of acute creatine supplementation on multiple sprint cycling and running performance in rugby players. Ahmun RP, Tong RJ, Grimshaw PN. J Strength Cond Res. 2005 Feb;19(1):92-7. 275. Effects of creatine monohydrate supplementation on body composition and strength indices in experienced resistance trained women. Ferguson TB, Syrotuik DG. J Strength Cond Res. 2006 Nov;20(4):939-46. 276. Creatine fails to augment the benefits from resistance training in patients with HIV infection: a randomized, double-blind, placebo-controlled study. Sakkas GK, Mulligan K, Dasilva M, Doyle JW, Khatami H, Schleich T, KentBraun JA, Schambelan M. PLoS One. 2009;4(2):e4605. Epub 2009 Feb 26. 277. Effect of creatine supplementation on body composition and performance: a meta-analysis.Branch JD. Int J Sport Nutr Exerc Metab. 2003 Jun;13(2):198-226. 278. The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels. Spillane M, Schoch R, Cooke M, Harvey T, Greenwood M, Kreider R, Willoughby DS. J Int Soc Sports Nutr. 2009 Feb 19;6:6. 279. Non-Enzymatic Hydrolysis of Creatine Ethyl Ester. Katseres NS, Reading DW, Shayya L, Dicesare JC, Purser GH. Biochem Biophys Res Commun. 2009 Jun 11. [Epub ahead of print] 280. The effects of creatine pyruvate and creatine citrate on performance during high intensity exercise. Jäger R, Metzger J, Lautmann K, Shushakov V, Purpura M, Geiss KR, Maassen N. J Int Soc Sports Nutr. 2008 Feb 13;5:4. 281. Comparison of new forms of creatine in raising plasma creatine levels. Jäger R, Harris RC, Purpura M, Francaux M. J Int Soc Sports Nutr. 2007 Nov 12;4:17. 282. The effects of creatine pyruvate and creatine citrate on performance during high intensity exercise. Jäger R, Metzger J, Lautmann K, Shushakov V, Purpura M, Geiss KR, Maassen N. J Int Soc Sports Nutr. 2008 Feb 13;5:4. 283. Edustusmelojat testasivat kreatiinipyruvaatin. Nuuttilla S. Suomen Urheilulehti 2000, 23(S); 4. 284. Comparison of new forms of creatine in raising plasma creatine levels. Jäger R, Harris RC, Purpura M, Francaux M. J Int Soc Sports Nutr. 2007 Nov 12;4:17. 285. Magnesium-creatine supplementation effects on body water. Brilla LR, Giroux MS, Taylor A, Knutzen KM. Metabolism. 2003 Sep;52(9):1136-40. 286. Mg2+-creatine chelate and a low-dose creatine supplementation regimen improve exercise performance. Selsby JT, DiSilvestro RA, Devor ST. J Strength Cond Res. 2004 May;18(2):311-5. 287. Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis. Greenhaff PL, Bodin K, Soderlund K, Hultman E. Am J Physiol. 1994 May;266(5 Pt 1):E725-30. 288. Creatine supplementation: a comparison of loading and maintenance protocols on creatine uptake by human skeletal muscle. Preen, D. et al. Int J Sport Nutr Exerc Metab. 13: 97-111 (2003). 289. Creatine supplementation: a comparison of loading and maintenance protocols on creatine uptake by human skeletal muscle. Preen D, Dawson B, Goodman C, Beilby J, Ching S. Int J Sport Nutr Exerc Metab. 2003 Mar;13(1):97-111. 290. Long-term creatine supplementation is safe in aged patients with Parkinson disease. Bender A, Samtleben W, Elstner M, Klopstock T. Nutr Res. 2008 Mar;28(3):172-8. 291. DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology. Labrie F, Luu-The V, Labrie C, Simard J. Front Neuroendocrinol. 2001 Jul;22(3):185-212. 292. Dehydroepiandrosterone and its metabolites: Differential effects on androgen receptor trafficking and transcriptional activity. Qianxing Mo, Shi-fang Lu and Neal G. Simon. The Journal of Steroid Biochemistry and Molecular Biology. Volume 99, Issue 1, April 2006, Pages 50-58 293. Impact of DHEA(S) and cortisol on immune function in aging: a brief review. Buford TW, Willoughby DS. Appl Physiol Nutr Metab. 2008 Jun;33(3):429-33. 294. Actions of dehydroepiandrosterone and its sulfate in the central nervous system: effects on cognition and emotion in animals and humans. Wolf OT, Kirschbaum C. Brain Res Brain Res Rev. 1999 Nov;30(3):264-88. Review. 295. Effect of DHEA on Abdominal Fat and Insulin Action in Elderly Women and Men A Randomized Controlled Trial Dennis T. Villareal, MD; John O. Holloszy, MD. JAMA. 2004;292:2243-2248. 296. Anti-glucocorticoid effects of dehydroepiandrosterone (DHEA). Kalimi M et al. Mol Cell Biochem 131: 99-104, 1994 297. Effects of aging on dehydroepiandrosterone sulfate in relation to fasting insulin levels and body composition assessed by bioimpedance analysis. Denti L, Pasolini G, Sanfelici L, et al. Metabolism 1997, 46(7):826-32. 298. Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80- year old men. Belanger A et al. J Clin Endocrinol Metab 79: 1086-90, 1994 299. Replacement and supplementation of DHEA–is it a wellness hormone? Brückel J. MMW Fortschr Med. 2005 Feb 17;147(7):30-2. Review 300. DHEA therapy for women: effect on sexual function and wellbeing. Panjari M, Davis SR. Hum Reprod Update. 2007 May-Jun;13(3):239-48. Epub 2007 Jan 5. 301. Dehydroepiandrosterone reduces serum low density lipoprotein levels and body fat but does not alter insulin sensitivity in normal men. Nestler JE, Barlascini CO, Clore JN, Blackard WG. J Clin Endocrinol Metab. 1988 Jan;66(1):57-61. 302. Supplementation with DHEA: effect on muscle size, strength, quality of life, and lipids Dayal M, Sammel MD, Zhao J, Hummel AC, Vandenbourne K, Barnhart KT. J Womens Health (Larchmt). 2005 Jun;14(5):391-400. 303. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. Morales AJ, Nolan JJ, Nelson JC, Yen SS. J Clin Endocrinol Metab. 1994 Jun;78(6):1360-7. 304. DHEA enhances effects of weight training on muscle mass and strength in elderly women and men. Villareal DT, Holloszy JO. Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E1003-8. Epub 2006 Jun 20. 305. Dehydroepiandrosterone reduces serum low density lipoprotein levels and body fat but does not alter insulin sensitivity in normal men. Nestler JE, Barlascini CO, Clore JN, Blackard WG. J Clin Endocrinol Metab. 1988 Jan;66(1):57-61. 306. DHEA enhances effects of weight training on muscle mass and strength in elderly women and men. Dennis T. Villareal and John O. Holloszy. Am J Physiol Endocrinol Metab 291:1003-1008, 2006. 307. Effect of oral DHEA on serum testosterone and adaptations to resistance training in young men. Brown GA, Vukovich MD, Sharp RL, Reifenrath TA, Parsons KA, King DS. J Appl Physiol. 1999 Dec;87(6):2274-83. 308. Effects of dehydroepiandrosterone vs androstenedione supplementation in men. Wallace MB, Lim J, Cutler A, Bucci L. Med Sci Sports Exerc. 1999 Dec;31(12):1788-92. 309. Practical uses for ecdysteroids in mammals including humans: and update. Lafont R., Dinan L. Journal of Insect Science. 3:7 (2003) 310. The effect of Elton, leveton, fitoton and adapton on the work capacity of experimental animals. Azizov AP, Seifulla RD. 1998. Eksperimental’naya I Klinicheskaya Farmakologiya 61:61-63. 311. Effect of vitamin D3 and 20-hydroxyecdysone on the content of ATP, creatine phosphate, carnosine and Ca2+ in skeletal muscles. Kholodova IuD, Tuga? VA, Zimina VP. Ukr Biokhim Zh. 1997 May-Jun;69(3):3-9. 312. Effect of 20-hydroxyecdysone on the protein synthesis of pigs. Opletal, F. et al. Zivocisna Vyroba 42: 445-51 (1997). 313. Stimulation of growth and development in Japanese quails after oral administration of ecdysteroid-containing diet. Koudela, K. et al. Eur J Entomology 92: 349-354 (1995) 314. The combined use of Ecdisten and the product ‘Bodrost’ during training in cyclical types of sport. Simakin, S.Y. et al. Scientific Sports Bulletin, 1988. 2. 315. A comparative study of the anabolic action of ecdysten, leveton and Prime Plus, preparations of plant origin. Gadzhieva RM, Portugalov SN, Paniushkin VV, Kondrat’eva II. Eksp Klin Farmakol. 1995 Sep-Oct;58(5):46-8. 316. The action of methandrostenolone and ecdysterone on the physical endurance of animals and on protein metabolism in the skeletal muscles. Chermnykh NS, Shimanovski? NL, Shutko GV, Syrov VN. Farmakol Toksikol. 1988 Nov-Dec;51(6):57-60. 317. Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males. Wilborn CD, Taylor LW, Campbell BI, Kerksick C, Rasmussen CJ, Greenwood M, Kreider RB. J Int Soc Sports Nutr. 2006 Dec 13;3:19-27. 318. Insect hormones – ecdysteroids: their presence and actions in vertebrates. Slama K, Lafont R. Eur J Entomology 92: 355-77 (1995). 319. Therapeutic applications of fenugreek. Basch E, Ulbricht C, Kuo G. Altern Med Rev. 2003 Feb;8(1):20-7. 320. Fattening practices among Moroccan Saharawi women. Rguibi M, Belahsen R. East Mediterr Health J. 2006 Sep;12(5):619-24. 321. Hydroxyisoleucine: a novel amino acid potentiator of insulin action. Sauvaire Y et al. Diabetes 47:206-10. (1998) 322. Effect of fenugreek seeds on intravenous glucose disposition in non-insulin dependant diabetic patients. Raghuram TC et al. Phytother Res 8:83-6 (1994) 323. Effect of Trigonela foenum graceum on blood glucose levels in normal and alloxan-diabetic mice. Ajabnoor MA et al. Ethnopharmacol 22:45-49 (1988) 324. Therapeutic applications of Fenugreek. Basch E et al. Alt Med Rev 8(1): 20-27 (2003) 325. The effect of an ethanol extract derived from fenugreek (Trigonela foenum graceum) on bile acid absorption and cholesterol levels in rats. Stark A. et al. Br J Nutr 69:277-87 (1993) 326. Diosgenin–a growth stimulator of mammary gland of ovariectomized mouse. Aradhana. Rao AR. Kale RK. (1992) Indian Journal of Experimental Biology, 30(5):367-70 327. Rat growth-hormone release stimulators from fenugreek seeds. Shim SH, Lee EJ, Kim JS, Kang SS, Ha H, Lee HY, Kim C, Lee JH, Son KH. Chem Biodivers. 2008 Sep;5(9):1753-61. 328. The addition of fenugreek extract (Trigonella foenum-graecum) to glucose feeding increases muscle glycogen resynthesis after exercise. Ruby BC, Gaskill SE, Slivka D, Harger SG. Amino Acids. 2005 Feb;28(1):71-6. Epub 2004 Dec 2 329. Effects of fenugreek seeds (Trigonella foenum greaecum) extract on endurance capacity in mice. Ikeuchi M, Yamaguchi K, Koyama T, Sono Y, Yazawa K. J Nutr Sci Vitaminol (Tokyo). 2006 Aug;52(4):287-92. maguchi K, Koyama T, Sono Y, Yazawa K. J Nutr Sci Vitaminol (Tokyo). 2006 Aug;52(4):287-92. 330. Omega-3 fatty acids, exercise, physical activity and athletics. Simopoulos AP. World Rev Nutr Diet. 2008;98:23- 50. Review. 331. Omega-3 polyunsaturated fatty acids and human health outcomes. Calder PC, Yaqoob P. Biofactors. 2009 MayJun;35(3):266-72. 332. Roles of unsaturated fatty acids (especially omega-3 fatty acids) in the brain at various ages and during ageing. Bourre JM. J Nutr Health Aging. 2004;8(3):163-74. Review. 333. Fish oil and the management of hypertriglyceridemia.Mattar M, Obeid O. Nutr Health. 2009;20(1):41-9. Review. 334. The effect of omega-3 fatty acids on risk factors for cardiovascular diseases. Yam D, Bott-Kanner G, Genin I, Shinitzky M, Klainman E. Harefuah. 2001 Dec;140(12):1156-8, 1230. 335. Fish oil fatty acids improve postprandial vascular reactivity in healthy men. Armah CK, Jackson KG, Doman I, James L, Cheghani F, Minihane AM. Clin Sci (Lond). 2008 Jun;114(11):679-86 336. Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes. Rizza S, Tesauro M, Cardillo C, Galli A, Iantorno M, Gigli F, Sbraccia P, Federici M, Quon MJ, Lauro D. Atherosclerosis. 2009 Mar 19 337. Fish consumption, omega 3 fatty acids and cardiovascular disease. The science and the clinical trials. Galli C, Risé P. Nutr Health. 2009;20(1):11-20. Review. 338. Omega-3 fatty acids from fish oils and cardiovascular disease. Holub DJ, Holub BJ. Mol Cell Biochem. 2004 Aug;263(1-2):217-25. 339. Evidence for the cardioprotective effects of omega-3 Fatty acids. Carroll DN, Roth MT. Ann Pharmacother. 2002 Dec;36(12):1950-6. 340. Omega-3 fatty acids and inflammation. Mori TA, Beilin LJ. Curr Atheroscler Rep. 2004 Nov;6(6):461-7. Review 341. Therapeutic potential of n-3 polyunsaturated fatty acids in disease. Fetterman JW Jr, Zdanowicz MM. Am J Health Syst Pharm. 2009 Jul 1;66(13):1169-79. 342. Fish oil and inflammatory disease: is asthma the next target for n-3 fatty acid supplements?. Stephensen, C.B. 2004. Nutrition Reviews. 62(12):486-9. 343. Cognitive and physiological effects of Omega-3 polyunsaturated fatty acid supplementation in healthy subjects. Fontani G, Corradeschi F, Felici A, Alfatti F, Migliorini S, Lodi L. Eur J Clin Invest. 2005 Nov;35(11):691-9. 344. The pathophysiology and treatment of cancer cachexia. Barber MD. Nutr Clin Pract. 2002 Aug;17(4):203-9. 345. Cancer cachexia and its treatment with fish-oil-enriched nutritional supplementation. Barber MD. Nutrition. 2001 Sep;17(9):751-5. Review. 346. Omega-3 fatty acids, exercise, physical activity and athletics. Simopoulos AP. World Rev Nutr Diet. 2008;98:23- 50. Review. 347. Anti-obesity effects of long-chain omega-3 polyunsaturated fatty acids. Buckley JD, Howe PR. Obes Rev. 2009 May 12. [Epub ahead of print] 348. Dietary fish oil alters cardiomyocyte Ca2+ dynamics and antioxidant status. Jahangiri A, Leifert WR, Kind KL, McMurchie EJ. Free Radic Biol Med. 2006 May 1;40(9):1592-602. Epub 2006 Jan 18. 349. Supplementation with omega-3 polyunsaturated fatty acids augments brachial artery dilation and blood flow during forearm contraction. Walser B, Giordano RM, Stebbins CL. Eur J Appl Physiol. 2006 Jun;97(3):347-54. Epub 2006 Apr 25. 350. The effects of ingestion of omega-3 fatty acids on perceived pain and external symptoms of delayed onset muscle soreness in untrained men. Tartibian B, Maleki BH, Abbasi A. Clin J Sport Med. 2009 Mar;19(2):115-9. 351. Fish oil supplementation reduces severity of exercise-induced bronchoconstriction in elite athletes. Mickleborough TD, Murray RL, Ionescu AA, Lindley MR. Am J Respir Crit Care Med. 2003 Nov 15;168(10):1181-9. Epub 2003 Aug 6. 352. Omega-3 fatty acids, exercise, physical activity and athletics. Simopoulos AP. World Rev Nutr Diet. 2008;98:23- 50. Review. 353. DHA-rich fish oil lowers heart rate during submaximal exercise in elite Australian Rules footballers. Buckley JD, Burgess S, Murphy KJ, Howe PR. J Sci Med Sport. 2009 Jul;12(4):503-507. Epub 2008 Jun 13. 354. Fish oil reduces heart rate and oxygen consumption during exercise. Peoples GE, McLennan PL, Howe PR, Groeller H. J Cardiovasc Pharmacol. 2008 Dec;52(6):540-7. 355. Effect of n-3 fatty acids on free Tryptophan and exercise fatigue. Huffman DM et al. Eur J Appl Physiol 2004 Aug; 92(4-5): 584-91 Epub. 356. The role of fish oil in hypertension. Yang H, Kenny A. Conn Med. 2007 Oct;71(9):533-8. 357. Gamma-oryzanol: an important component in rice brain oil. Scavariello EM, Arellano DB. Arch Latinoam Nutr. 1998 Mar;48(1):7-12 358. Effects of gamma-oryzanol on serum lipids and apolipoproteins in dyslipidemic schizophrenics receiving major tranquilizers. Sasaki J, Takada Y, Handa K, Kusuda M, Tanabe Y, Matsunaga A, Arakawa K. Clin Ther. 1990 MayJun;12(3):263-8. 359. Effects of gamma-oryzanol on gastric lesions and small intestinal propulsive activity in mice. Ichimaru Y, Moriyama M, Ichimaru M, Gomita Y. Nippon Yakurigaku Zasshi. Dec1984;84(6):537-42 360. Clinical studies of oral administration of gamma-oryzanol on climacteric complaints and its syndrome. Murase Y, Iishima H. Obstet Gynecol Prac. 1963;12:147-9 361. Gamma oryzanol-plant sterol supplementation: metabolic, endocrine, and physiologic effects. Wheeler KB, Garleb KA. Int J Sport Nutr. Jun1991;1(2):170-7. 362. The effect of gamma-oryzanol on rat pituitary hormone secretion (author’s transl). Yamauchi J, Takahara J, Uneki T, Yakushiji W, Nakashima Y, Miyoshi M, Ofuji T. Nippon Naibunpi Gakkai Zasshi. 1980 Aug 20;56(8):1130-9. 363. Pituitary and thyroid hormone responses of heifers after ferulic acid administration. Gorewit RC. J Dairy Sci. 1983 Mar;66(3):624-9. 364. The effects of gamma-oryzanol supplementation during resistance exercise training. Fry AC, Bonner E, Lewis DL, et al. Int J Sport Nutr. Dec1997;7(4):318-29. 365. Glutamine and glutamate as vital metabolites. P. Newsholme et al. Braz J Med Biol Res 36(2): 153-163, 2003. 366. Is glutamine a conditionally essential amino acid? Lacey JM, Wilmore DW. Nutr Rev. 1990 Aug;48(8):297-309. Review. 367. Glutamine and glutamate as vital metabolites. P. Newsholme et al. Braz J Med Biol Res 36(2): 153-163, 2003. 368. Glutamine transport and its metabolic effects. Rennie MJ, Tadros L, Khogali S, Ahmed A, Taylor PM. J Nutr. 1994 Aug;124(8 Suppl):1503S-1508S. 369. Glutamine metabolism and transport in skeletal muscle and heart and their clinical relevance. Rennie MJ, Ahmed A, Khogali SE, Low SY, Hundal HS, Taylor PM. J Nutr. 1996 Apr;126(4 Suppl):1142S-9S. Review. 370. Glutamine: effects on the immune system, protein balance and intestinal functions] Roth E, Spittler A, Oehler R. Wien Klin Wochenschr. 1996;108(21):669-76. Review. 371. L-glutamine supplementation induces insulin resistance in adipose tissue and improves insulin signalling in liver and muscle of rats with diet-induced obesity. Prada PO, Hirabara SM, de Souza CT, Schenka AA, Zecchin HG, Vassallo J, Velloso LA, Carneiro E, Carvalheira JB, Curi R, Saad MJ. Diabetologia. 2007 Sep;50(9):1949-59. Epub 2007 Jun 29. 372. The effect of glutamine on prevention of glucocorticoid-induced skeletal muscle atrophy is associated with myostatin suppression. Salehian B, Mahabadi V, Bilas J, Taylor WE, Ma K. Metabolism. 2006 Sep;55(9):1239-47. 373. Interaction between glutamine availability and metabolism of glycogen, tricarboxylic acid cycle intermediates and glutathione. Rennie MJ, Bowtell JL, Bruce M, Khogali SE. J Nutr. 2001 Sep;131(9 Suppl):2488S-90S; discussion 2496S-7S. 374. Effect of oral glutamine on whole body carbohydrate storage during recovery from exhaustive exercise. Bowtell JL, Gelly K, Jackman ML, Patel A, Simeoni M, Rennie MJ. J Appl Physiol. 1999 Jun;86(6):1770-7. 375. Glutamine supplementation further enhances exercise-induced plasma IL-6. Hiscock N, Petersen EW, Krzywkowski K, Boza J, Halkjaer-Kristensen J, Pedersen BK. J Appl Physiol. 2003 Jul;95(1):145-8. Epub 2003 Feb 28. 376. The biological roles of exercise-induced cytokines: IL-6, IL-8, and IL-15. Nielsen AR, Pedersen BK. Appl Physiol Nutr Metab. 2007 Oct;32(5):833-9. 377. Glutamine and carbohydrate supplements reduce ammonemia increase during endurance field exercise. Carvalho-Peixoto J, Alves RC, Cameron LC. Appl Physiol Nutr Metab. 2007 Dec;32(6):1186-90. 378. Effects of supply with glutamine on antioxidant system and lipid peroxidation in patients with parenteral nutrition. Abilés J, Moreno-Torres R, Moratalla G, Castaño J, Pérez Abúd R, Mudarra A, Machado MJ, Planells E, Pérez de la Cruz A. Nutr Hosp. 2008 Jul-Aug;23(4):332-9. 379. The effects of oral glutamine supplementation on athletes after prolonged, exhaustive exercise. Castell LM, Newsholme EA. Nutrition. 1997 Jul-Aug;13(7-8):738-42. 380. Glutamine and the effects of exhaustive exercise upon the immune response. Castell LM, Newsholme EA. Can J Physiol Pharmacol. 1998 May;76(5):524-32. Review. 381. Enteral glutamine increases growth and absorptive capacity of intestinal mucosa in the malnourished rat. Wirén M, Magnusson KE, Larsson J. Scand J Gastroenterol. 1995 Feb;30(2):146-52. 382. Glutamine supplementation. Heal the gut, help the patient. Savy GK. J Infus Nurs. 2002 Jan-Feb;25(1):65-9. Review. 383. Effect of oral glutamine on whole body carbohydrate storage during recovery from exhaustive exercise. Bowtell JL, Gelly K, Jackman ML, Patel A, Simeoni M, Rennie MJ. J Appl Physiol. 1999 Jun;86(6):1770-7. 384. Effect of exercise on protein turnover in man. Rennie MJ, Edwards RH, Krywawych S, Davies CT, Halliday D, Waterlow JC, Millward DJ. Clin Sci (Lond). 1981 Nov;61(5):627-39. 385. Whole body and skeletal muscle glutamine metabolism in healthy subjects. Mittendorfer B, Volpi E, Wolfe RR. Am J Physiol Endocrinol Metab. 2001 Feb;280(2):E323-33. 386. Plasma glutamine response to enteral administration of glutamine in human volunteers (free glutamine versus protein-bound glutamine). Boza JJ, Maire J, Bovetto L, Ballèvre O. Nutrition. 2000 Nov-Dec;16(11-12):1037-42. 387. Peptide glutamine supplementation for tolerance of intermittent exercise in soccer players. Favano A, SantosSilva PR, Nakano EY, Pedrinelli A, Hernandez AJ, Greve JM. Clinics (Sao Paulo). 2008 Feb;63(1):27-32. 388. Addition of glutamine to essential amino acids and carbohydrate does not enhance anabolism in young human males following exercise. Wilkinson SB, Kim PL, Armstrong D, Phillips SM. Appl Physiol Nutr Metab. 2006 Oct;31(5):518-29. 389. Acute L-glutamine ingestion does not improve maximal effort exercise. Haub MD, Potteiger JA, Nau KL, Webster MJ, Zebas CJ. J Sports Med Phys Fitness. 1998 Sep;38(3):240-4. 390. No effect of glutamine supplementation and hyperoxia on oxidative metabolism and performance during high-intensity exercise. Marwood S, Bowtell J. J Sports Sci. 2008 Aug;26(10):1081-90. 391. The effects of high-dose glutamine ingestion on weightlifting performance. Antonio J, Sanders MS, Kalman D, Woodgate D, Street C. J Strength Cond Res. 2002 Feb;16(1):157-60. 392. Acute L-glutamine ingestion does not improve maximal effort exercise. Haub MD, Potteiger JA, Nau KL, Webster MJ, Zebas CJ. J Sports Med Phys Fitness. 1998 Sep;38(3):240-4. 393. Dosing and efficacy of glutamine supplementation in human exercise and sport training. Gieeson M. J Nutr. 2008 Oct;138(10: 2045S-2049S. 394. Exploring the potential ergogenic effects of glycerol hyperhydration. Nelson JL, Robergs RA. Sports Med. 2007;37(11) 981-1000. 395. Hyperhydrating with glycerol: implications for athletic performance. Wagner DR. J Am Diet Assoc. 1999 Feb;99(2);207-12. 396. Comparison of glycerol and water hydration regimens on tennis-related performance. Magal M, Webster MJ, Sistrunk LE, Whitehead MT, Evans RK, Boyd JC. Med Sci Sports Exerc. 2003 Jan;35(1):150-6. 397. Oral glycerine has a negligible effect on plasma glucose and insulin in normal subjects. Diabetes 2002;51(Supplement 2):A602. 398. Comparison of the effects of pre-exercise feeding of glucose, glycerol and placebo on endurance and fuel homeostasis in man. Gleeson M, Maughan RJ, Greenhaff PL. Eur J Appl Physiol Occup Physiol. 1986;55(6):645-53. 399. The effect of glycerol hyperhydration on olympic distance triathlon performance in high ambient temperatures. Coutts A, Reaburn P, Mummery K, Holmes M. Int J Sport Nutr Exerc Metab. 2002 Mar;12(1):105-19. 400. Effects of glycerol-induced hyperhydration prior to exercise in the heat on sweating and core temperature. Lyons TP, Riedesel ML, Meuli LE, Chick TW. Med Sci Sports Exerc. 1990 Aug;22(4):477-83 401. Glycerol hyperhydration improves cycle time trial performance in hot humid conditions. Hitchins S, Martin DT, Burke L, Yates K, Fallon K, Hahn A, Dobson GP. Eur J Appl Physiol Occup Physiol. 1999 Oct;80(5):494-501. 402. Hyperhydration and glycerol: thermoregulatory effects during exercise in hot climates. Latzka WA, Sawka MN. Can J Appl Physiol. 2000 Dec;25(6):536-45. 403. Cerebral dehydration action of glycerol. Tourtellotte WW et al. Clin Pharmacol Ther 13: 159-171, 1972. 404. The effect of glycerol hyperhydration on olympic distance triathlon performance in high ambient temperatures. Coutts A, Reaburn P, Mummery K, Holmes M. Int J Sport Nutr Exerc Metab. 2002 Mar;12(1):105-19 405. Hyperhydration: thermoregulatory effects during compensable exercise-heat stress. Latzka WA, Sawka MN, Montain SJ, Skrinar GS, Fielding RA, Matott RP, Pandolf KB. J Appl Physiol. 1997 Sep;83(3):860-6. 406. Hyperhydration: tolerance and cardiovascular effects during uncompensable exercise-heat stress. Latzka WA, Sawka MN, Montain SJ, Skrinar GS, Fielding RA, Matott RP, Pandolf KB. J Appl Physiol. 1998 Jun;84(6):1858-64. 407. The ergogenic potential of arginine. B. Campbell, P. La Bounty, M. Roberts. JISSN 1(2):35-38 (2004) 408. The effects of short-term alpha-ketoisocaproic acid supplementation on exercise performance: a randomized controlled trial. Yarrow JF, Parr JJ, White LJ, Borsa PA, Stevens BR. J Int Soc Sports Nutr. 2007 Jul 13;4:2. 409. High-intensity dynamic human muscle performance enhanced by a metabolic intervention. Stevens BR, Godfrey MD, Kaminski TW, Braith RW. Med Sci Sports Exerc. 2000 Dec;32(12):2102-8 410. Glycine-arginine-alpha-ketoisocaproic acid improves performance of repeated cycling sprints. Buford BN, Koch AJ. Med Sci Sports Exerc. 2004 Apr;36(4):583-7. 411. Propionyl-L-carnitine dilates human subcutaneous arteries through an endothelium-dependent mechanism. Cipolla MJ, Nicoloff A, Rebello T, Amato A, Porter JM. J Vasc Surg. 1999 Jun;29(6):1097-103. 412. Is glycine effective against elevated blood pressure? Hafidi ME et al. Curr Opin Clin Nutr Metab Care 2006, 9:26-31 413. Therapeutic Effects of L-Carnitine and Propionyl-L-carnitine on Cardiovascular Diseases: A Review. Roberto Ferrari, E. et al. Ann. N.Y. Acad. Sci. 1033: 79–91 (2004) 414. Propionyl-L-carnitine. Wiseman LR, Brogden RN. Drugs Aging. 1998 Mar;12(3):243-8; discussion 249-50. 415. Ergogenic effect of glycine and niacin separately and in combination. Hilsendager D, Karpovich PV. Res Q. 1964 Oct;35:SUPPL:389-92. 416. Glycine propionyl-L-carnitine produces enhanced anaerobic work capacity with reduced lactate accumulation in resistance trained males. Patrick L Jacobs. et al. Journal of the International Society of Sports Nutrition 2009, 6:9 417. Effect of glycine propionyl-L-carnitine on aerobic and anaerobic exercise performance. Smith WA, Fry AC, Tschume LC, Bloomer RJ. Int J Sport Nutr Exerc Metab. 2008 Feb;18(1):19-36. 418. Glycine propionyl-L-carnitine increases plasma nitrate/nitrite in resistance trained men. Bloomer RJ, Smith WA, Fisher-Wellman KH. J Int Soc Sports Nutr. 2007 Dec 3;4:22. 419. Effects of excess dietary leucine and leucine catabolites on growth and immune responses in weaning pigs. Gatnau, R et al. J. Anim. Sci. 73(1): 159-65. 420. Mechanism of attenuation by beta-hydroxy-beta-methylbutyrate of muscle protein degradation induced by lipopolysaccharide. Russell ST, Tisdale MJ. Mol Cell Biochem. 2009 Apr 30. [Epub ahead of print] 421. Beta-hydroxy-beta-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways. Kornasio R. et al. Biochem Biophys Acta. 2009 Jan 3 [epub]. 422. Effect of beta-hydroxy-beta-methylbutyrate (HMB) on protein metabolism in whole body and in selected tissues. Holecek M, Muthny T, Kovarik M, Sispera L. Food Chem Toxicol. 2009 Jan;47(1):255-9. Epub 2008 Nov 21. 423. Effects of beta-hydroxy-beta-methylbutyrate on muscle damage after a prolonged run. Knitter AE, Panton L, Rathmacher JA, Petersen A, Sharp R. J Appl Physiol. 2000 Oct;89(4):1340-4. 424. Effects of nine weeks of beta-hydroxy-beta- methylbutyrate supplementation on strength and body composition in resistance trained men. Thomson JS, Watson PE, Rowlands DS. J Strength Cond Res. 2009 May;23(3):827-35. 425. Effects of beta-hydroxy-beta-methylbutyrate supplementation during resistance training on strength, body composition, and muscle damage in trained and untrained young men: a meta-analysis. Rowlands DS, Thomson JS. J Strength Cond Res. 2009 May;23(3):836-46. 426. Effects of ß-hydroxy-ß-methylbutyrate (HMB) on aerobic performance components and body composition in college students. Lamboley, C.R., D. Royer, and I.J. Dionne. Int. J. Sport Nutr. Exerc. Metab. 17:56-69 (2007) 427. Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities. Xin ZC, Kim EK, Lin CS, Liu WJ, Tian L, Yuan YM, Fu J. Asian J Androl. 2003 Mar;5(1):15-8. 428. Effect of icariin on cyclic GMP levels and on the mRNA expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in penile cavernosum. Jiang Z, Hu B, Wang J, Tang Q, Tan Y, Xiang J, Liu J. J Huazhong Univ Sci Technolog Med Sci. 2006;26(4):460-2. 429. Effects of icariin on hypothalamic-pituitary-adrenal axis action and cytokine levels in stressed Sprague-Dawley rats. Pan Y, Zhang WY, Xia X, Kong LD. Biol Pharm Bull. 2006 Dec;29(12):2399-403. 430. Protective effects of icariin against learning and memory deficits induced by aluminium in rats. Luo Y, Nie J, Gong QH, Lu YF, Wu Q, Shi JS. Clin Exp Pharmacol Physiol. 2007 Aug;34(8):792-5. 431. Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells. Chen KM, Ge BF, Ma HP, Liu XY, Bai MH, Wang Y. Pharmazie. 2005 Dec;60(12):939-42. 432. Standardization and evaluation of botanical mixtures: lessons from a traditional Chinese herb, Epimedium, with oestrogenic properties. Yong EL, Wong SP, Shen P, Gong YH, Li J, Hong Y. Novartis Found Symp. 2007;282:173-88; discussion 188-91, 212-8. 433. Determination of rat urinary metabolites of icariin in vivo and estrogenic activities of its metabolites on MCF-7 cells. Liu J, Ye H, Lou Y. Pharmazie. 2005 Feb;60(2):120-5. 434. Effects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats. Liu WJ, Xin ZC, Xin H, Yuan YM, Tian L, Guo YL. Asian J Androl. 2005 Dec;7(4):381-8. 435. Effects of yang-restoring herb medicines on the levels of plasma corticosterone, testosterone and triiodothyronine. Kuang AK, Chen JL, Chen MD. Zhong Xi Yi Jie He Za Zhi. 1989 Dec;9(12):737-8, 710. 436. A new herbal combination, Etana, for enhancing erectile function: an efficacy and safety study in animals. Qinna N, Taha H, Matalka KZ, Badwan AA. Int J Impot Res. 2009 Jun 4. [Epub ahead of print] 437. Ipriflavone, a synthetic phytoestrogen, enhances intestinal calcium transport in vitro. Arjmandi BH, Khalil DA, Hollis BW. Calcif Tissue Int. 2000 Sep;67(3):225-9. 438. Ipriflavone. Kitatani K, Morii H. Nippon Rinsho. 1998 Jun;56(6):1537-43. 439. Overview of clinical studies with ipriflavone. Attila BK. Acta Pharm Hung. 1995 Nov;65(6):223-8. Review. 440. Anabolic-weight-gain promoting compositions containing isoflavone derivatives and method using same. 1974. Feuer, L. U.S. Patent # 4,163,746. 441. Feuer L, Farkas L, Nogradi M, et al. Metabolic 5-methyl-isoflavone-derivatives, process for the preparation thereof and compositions containing the same. United States Patent 4,163,746, August 7, 1979. 442. Ipriflavone modulates IGF-I but is unable to restore bone in rats. Deyhim F, Smith BJ, Soung DY, Juma S, Devareddy L, Arjmandi BH. Phytother Res. 2005 Feb;19(2):116-20. 443. Efficacy of ipriflavone in established osteoporosis and long-term safety. Agnusdei D, Bufalino L. Calcif Tissue Int. 1997;61 Suppl 1:S23-7. 444. Dietary Protein Impact on Glycemic Control during Weight Loss. Donald K. Layman and Jamie I. Baum. J. Nutr. 134: 968S–973S, 2004 445. Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway. Anthony JC, Yoshizawa F, Anthony TG, Vary TC, Jefferson LS, Kimball SR. J Nutr. 2000 Oct;130(10):2413-9. 446. Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle. Dreyer HC, Drummond MJ, Pennings B, Fujita S, Glynn EL, Chinkes DL, Dhanani S, Volpi E, Rasmussen BB. Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E392-400. Epub 2007 Dec 4. 447. Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. Norton LE, Layman DK. J Nutr. 2006 Feb;136(2):533S-537S. 448. Role of leucine in protein metabolism during exercise and recovery. Layman DK. Can J Appl Physiol. 2002 Dec;27(6):646-63. 449. Relationship between leucine oxidation and oxygen consumption during steady-state exercise. Lamont LS, McCullough AJ, Kalhan SC. Med Sci Sports Exerc. 2001 Feb;33(2):237-41. 450. The effects of BCAA and leucine supplementation and lower-body resistance exercise on the ERK 1/2 MAPK pathway signal transduction. Bill Campbell et al. JISSN 2008, 5 (Suppl 1): P19 451. Effects of dietary leucine supplementation on exercise performance. Crowe MJ, Weatherson JN, Bowden BF. Eur J Appl Physiol. 2006 Aug;97(6):664-72. Epub 2005 Oct 29. 452. Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects. Rene´ Koopman et al. Am J Physiol Endocrinol Metab 288: E645–E653, 2005. 453. Leucine supplementation does not enhance acute strength or running performance but affects serum amino acid concentration. Pitkänen HT, Oja SS, Rusko H, Nummela A, Komi PV, Saransaari P, Takala T, Mero AA. Amino Acids. 2003 Jul;25(1):85-94. 454. Leucine supplementation and intensive training. Mero A. Sports Med. 1999 Jun;27(6):347-58. Review. 455. Stimulation of muscle anabolism by resistance exercise and ingestion of leucine plus protein. Tipton KD, Elliott TA, Ferrando AA, Aarsland AA, Wolfe RR. Appl Physiol Nutr Metab. 2009 Apr;34(2):151-61. 456. Effects of Eurycoma longifolia Jack (Tongkat Ali) on the initiation of sexual performance of inexperienced castrated male rats. Ang HH, Cheang HS, Yusof AP. Exp Anim. 2000 Jan;49(1):35-8. 457. Evaluation of the potency activity of aphrodisiac in Eurycoma longifolia Jack. Ang HH, Ikeda S, Gan EK. Phytother Res. 2001 Aug;15(5):435-6. 458. Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia. Kuo PC, Damu AG, Lee KH, Wu TS. Bioorg Med Chem. 2004 Feb 1;12(3):537-44. 459. Biologically Active Quassinoids and Their Chemistry: Potential Leads for Drug Design Z. Guo1, S. Vangapandu et al. Current Medicinal Chemistry, 2005, 12, 173-190 173 460. The ergogenic effects of Eurycoma longifolia Jack: A Pilot Study. S. Hamzah et al. 2003;37;464-470 Br. J. Sports Med. 461. Effect of Eurycoma longifolia Extract on Anabolic Balance During Endurance Exercise. Talbott S, et al. Journal of the International Society of Sports Nutrition. 3 (1)S1-S29, 2006 462. Anabolic-weight-gain promoting compositions containing isoflavone derivatives and method using same. 1974. Feuer, L. U.S. Patent # 4,163,746. 463. Feuer L, Farkas L, Nogradi M, et al. Metabolic 5-methyl-isoflavone-derivatives, process for the preparation thereof and compositions containing the same. United States Patent 4,163,746, August 7, 1979. 464. The effects of 5-methyl-7-methoxyisoflavone on body composition and performance in college-aged men. Incledon, Thomas, Van Gammeren, Darin1, Antonio, Jose, Medicine & Science in Sports & Exercise:Volume 33(5) Supplement 1May 2001p S338 465. Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males. Wilborn CD, Taylor LW, Campbell BI, Kerksick C, Rasmussen CJ, Greenwood M, Kreider RB. J Int Soc Sports Nutr. 2006 Dec 13;3:19-27. 466. N-acetyl-L-Cysteine Promotes T Cell Mediated Immunity In Allogeneic Settings IN VIVO And IN VITRO. H. Karlsson, S. Nava, M. Remberger, Z. Hassan, M. Hassan, O. Ringden Biology of Blood and Marrow Transplantation, Volume 15, Issue 2, Pages 127-127 467. The comparison of antioxidant and haematological properties of N-acetylcysteine and alpha-lipoic acid in physically active males. Zembron-Lacny A, Slowinska-Lisowska M, Szygula Z, Witkowski K, Szyszka K. Physiol Res. 2008 Dec 17. 468. Effects of N-acetylcysteine on respiratory muscle fatigue during heavy exercise. Kelly MK, Wicker RJ, Barstow TJ, Harms CA. Respir Physiol Neurobiol. 2009 Jan 1;165(1):67-72. Epub 2008 Oct 17. 469. Effect of respiratory muscle fatigue on subsequent exercise performance. Mador MJ, Acevedo FA. J Appl Physiol. 1991 May;70(5):2059-65. 470. N-acetylcysteine enhances muscle cysteine and glutathione availability and attenuates fatigue during prolonged exercise in endurance-trained individuals. Medved I, Brown MJ, Bjorksten AR, Murphy KT, Petersen AC, Sostaric S, Gong X, McKenna MJ. J Appl Physiol. 2004 Oct;97(4):1477-85. Epub 2004 Jun 11 471. Effects of N-acetylcysteine on glutathione oxidation and fatigue during handgrip exercise. Matuszczak Y, Farid M, Jones J, Lansdowne S, Smith MA, Taylor AA, Reid MB. Muscle Nerve. 2005 Nov;32(5):633-8. 472. N-acetylcysteine inhibits muscle fatigue in humans. Reid MB, Stokiç DS, Koch SM, Khawli FA, Leis AA. J Clin Invest. 1994 Dec;94(6):2468-74. 473. N-acetylcysteine attenuates the decline in muscle Na+,K+-pump activity and delays fatigue during prolonged exercise in humans. McKenna MJ, Medved I, Goodman CA, Brown MJ, Bjorksten AR, Murphy KT, Petersen AC, Sostaric S, Gong X. J Physiol. 2006 Oct 1;576(Pt 1):279-88. Epub 2006 Jul 13. 474. The Healing Power of Rainforest Herbs. Leslie Taylor. (2005) 475. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Schöttner M, Gansser D, Spiteller G. Planta Med. 1997 Dec;63(6):529-32. 476. Urtica dioicafor Treatment of Benign Prostatic Hyperplasia: A Prospective, Randomized, Double-Blind, placebo-controlled, Crossover Study. Mohammad Reza Safarinejad. Journal Of Herbal Pharmacotherapy, 1522-9106, Volume 5, Issue 4, 2006, Pages 1–11 477. Phospholipids and sports performance. Jäger R, Purpura M, Kingsley M. J Int Soc Sports Nutr. 2007 Jul 25;4:5. 478. The effects of phosphatidylserine on endocrine response to moderate intensity exercise. Starks MA, Starks SL, Kingsley M, Purpura M, Jäger R. J Int Soc Sports Nutr. 2008 Jul 28;5:11. 479. Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men. Monteleone P, Maj M, Beinat L, Natale M, Kemali D. Eur J Clin Pharmacol. 1992;42(4):385-8. 480. Effects of phosphatidylserine on exercise capacity during cycling in active males. Kingsley MI, Miller M, Kilduff LP, McEneny J, Benton D. Med Sci Sports Exerc. 2006 Jan;38(1):64-71. 481. Effects of phosphatidylserine on oxidative stress following intermittent running. Kingsley MI, Wadsworth D, Kilduff LP, McEneny J, Benton D. Med Sci Sports Exerc. 2005 Aug;37(8):1300-6. 482. The effects of phosphatidyl serine on markers of muscular stress in endurance runners. Fernholz KM et al. Med Sci Sport Exerc 2000, 32(5):s321. 483. The hormonal and perceptive effects of phosphatidylserine administration during two weeks of weight traininginduced over-training. Fahey TD et al. Biol Sport 15(2):135-44 (1998) 484. The role of ribose in human skeletal muscle metabolism. Dodd SL, Johnson CA, Fernholz K, St Cyr JA. Med Hypotheses. 2004;62(5):819-24. 485. ATP breakdown products in human skeletal muscle during prolonged exercise to exhaustion. Norman B, Sollevi A, Kaijser L, Jansson E. Clin Physiol. 1987 Dec;7(6):503-10. 486. Energetics of human muscle: exercise-induced ATP depletion. Taylor DJ, Styles P, Matthews PM, Arnold DA, Gadian DG, Bore P, Radda GK. Magn Reson Med. 1986 Feb;3(1):44-54. 487. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. Hellsten Y, Skadhauge L, Bangsbo J. Am J Physiol Regul Integr Comp Physiol. 2004 Jan;286(1):R182-8. 488. The effects of four weeks of ribose supplementation on body composition and exercise performance in healthy young male recreational bodybuilders. Van Gammeren D et al. Curr Ther Res 63(8), 486-95 (2002) 489. Effects of oral D-ribose supplementation on anaerobic capacity and selected metabolic markers in healthy males. Kreider RB, Melton C, Greenwood M, Rasmussen C, Lundberg J, Earnest C, Almada A. Int J Sport Nutr Exerc Metab. 2003 Mar;13(1):76-86. 490. Effects of ribose supplementation on repeated sprint performance in men. Berardi JM, Ziegenfuss TN. J Strength Cond Res. 2003 Feb;17(1):47-52. 491. Assessment of Hematological and Biochemical parameters with extended D-Ribose ingestion. Seifert J, Frelich A, Shecterle L, St Cyr J. J Int Soc Sports Nutr. 2008 Sep 15;5:13. 492. Contraceptives and other steroid drugs: their production from steroidal sapogenins.Fazli FR. Pak J Sci. 1968 JanMar;20(1 and 2):64-7. 493. The biological action of saponins in animal systems: a review. Francis G, Kerem Z, Makkar HP, Becker K. Br J Nutr. 2002 Dec;88(6):587-605. 494. The bioactivity of saponins: triterpenoid and steroidal lycosides. Rao AV. Gurfinkel DM. Drug Metab Drug Interact 2000;17(1-4):211-35 495. Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. Sauvaire Y, Ribes G, Baccou JC, Loubatieères-Mariani MM. Lipids. 1991 Mar;26(3):191-7. 496. Saponins: Properties, Applications and Processing. zlem Gl-stnda; Giuseppe Mazza. Critical Reviews in Food Science and Nutrition, Volume 47, Issue 3 March 2007 , pages 231 – 258 497. Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats. Son IS, Kim JH, Sohn HY, Son KH, Kim JS, Kwon CS. Biosci Biotechnol Biochem. 2007 Dec;71(12):3063-71. Epub 2007 Dec 7. 498. Cancer chemopreventive and therapeutic effects of diosgenin, a food saponin. Raju J, Mehta R. Nutr Cancer. 2009;61(1):27-35. 499. Diosgenin–a growth stimulator of mammary gland of ovariectomized mouse. Aradhana. Rao AR. Kale RK. (1992) Indian Journal of Experimental Biology, 30(5):367-70 500. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Komesaroff PA, Black CV, Cable V, Sudhir K. Climacteric. 2001 Jun;4(2):144-50. 501. Experimental study of the anabolic activity of 6-ketoderivatives of certain natural sapogenins. Syrov VN, Kurmukov AG. Farmakol Toksikol. 1976 Sep-Oct;39(5):631-5. 502. Induction of growth hormone release by dioscin from Dioscorea batatas DECNE. Lee HY, Jung DY, Ha H, Son KH, Jeon SJ, Kim C. J Biochem Mol Biol. 2007 Nov 30;40(6):1016-20. 503. Experimental study of the anabolic activity of 6-ketoderivatives of certain natural sapogenins. Syrov VN, Kurmukov AG. Farmakol Toksikol. 1976 Sep-Oct;39(5):631-5. 504. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Komesaroff PA, Black CV, Cable V, Sudhir K. Climacteric. 2001 Jun;4(2):144-50. 505. Sulfated polysaccharides of brown seaweed Cystoseira canariensis bind to serum myostatin protein. Ramazanov Z, Jimenez del Rio M, Ziegenfuss T. Acta Physiol Pharmacol Bulg. 2003;27(2-3):101-6. 506. Effects of an alleged myostatin-binding supplement and heavy resistance training on serum myostatin, muscle strength and mass, and body composition. Willoughby DS. Int J Sport Nutr Exerc Metab. 2004 Aug;14(4):461-72. 507. Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males. Wilborn CD, Taylor LW, Campbell BI, Kerksick C, Rasmussen CJ, Greenwood M, Kreider RB. J Int Soc Sports Nutr. 2006 Dec 13;3:19-27. 508. Sexual effects of puncturevine (Tribulus terrestris) extract (protodioscin): an evaluation using a rat model. Gauthaman K, Ganesan AP, Prasad RN. J Altern Complement Med. 2003 Apr;9(2):257-65. 509. Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats. Gauthaman K, Adaikan PG, Prasad RN. Life Sci. 2002 Aug 9;71(12):1385-96. 510. The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction–an evaluation using primates, rabbit and rat. Gauthaman K, Ganesan AP. Phytomedicine. 2008 Jan;15(1-2):44-54. 511. Distribution of steroidal saponins in Tribulus terrestris from different geographical regions. Dinchev D, Janda B, Evstatieva L, Oleszek W, Aslani MR, Kostova I. Phytochemistry. 2008 Jan;69(1):176-86. Epub 2007 Aug 23. 512. Tribestan effect on the concentration of some hormones in the serum of healthy subjects S. Milanov, A. Maleeva, M. Taskov RIRR – Radioisotope and Radioimmunological Laboratory, Sofia 513. The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction–an evaluation using primates, rabbit and rat. Gauthaman K, Ganesan AP. Phytomedicine. 2008 Jan;15(1-2):44-54. 514. The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men. Neychev VK, Mitev VI. J Ethnopharmacol. 2005 Oct 3;101(1-3):319-23. 515. The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players. Rogerson S, Riches CJ, Jennings C, Weatherby RP, Meir RA, Marshall-Gradisnik SM. J Strength Cond Res. 2007 May;21(2):348-53. 516. The effects of Tribulus terrestris on body composition and exercise performance in resistance-trained males. Antonio J, Uelmen J, Rodriguez R, Earnest C. Int J Sport Nutr Exerc Metab. 2000 Jun;10(2):208-15. 517. Magnesium, zinc, and chromium nutriture and physical activity. Henry C Lukaski. Am J Clin Nutr2000;72(suppl):585S–93S 518. Vitamin B6 deficiency can reduce fuel storage and utilization in physically trained rats. Choi EY, Cho YO. Int J Vitam Nutr Res. 2008 Mar;78(2):64-9. 519. Effects of a Novel Zinc-Magnesium Formulation on Hormones and Strength L.R. Brilla and Victor Conte. Journal of Exercise Physiology (Online) Volume 3 Number 4 October 2000. 520. Serum testosterone and urinary excretion of steroid hormone metabolites after administration of a high-dose zinc supplement. K Koehler. Eur J Clin Nutr 63, 65-70 (2009) 521. Effects of Zinc Magnesium Aspartate (ZMA) Supplementation on Training Adaptations and Markers of Anabolism and Catabolism. Wilborn CD, Kerksick CM et al. J Int Soc Sports Nutr. 2004 Dec 31;1(2):12-20.