Enzymes – WIKIBOLICS

<body><h1>Amylase</h1>Description:An amylase is an enzyme that catalyzes the hydrolysis of starch into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of digestion. Foods that contain large amounts of starch but little sugar, such as rice and potatoes, may acquire a slightly sweet taste as they are chewed because amylase degrades some of their starch into sugar. The pancreas and salivary gland make amylase (alpha amylase) to hydrolyze dietary starch into disaccharides and trisaccharides which are converted by other enzymes to glucose to supply the body with energy. Plants and some bacteria also produce amylase. Specific amylase proteins are designated by different Greek letters. All amylases are glycoside hydrolases and act on α-1,4-glycosidic bonds.History:In 1831, Erhard Friedrich Leuchs (1800–1837) described the hydrolysis of starch by saliva, due to the presence of an enzyme in saliva, “ptyalin”, an amylase. The modern history of enzymes began in 1833, when French chemists Anselme Payen and Jean-François Persoz isolated an amylase complex from germinating barley and named it “diastase”. It is from this term that all subsequent enzyme names tend to end in the suffix -ase. In 1862, Alexander Jakulowitsch Danilewsky (1838–1923) separated pancreatic amylase from trypsin.Saccharides are a food source rich in energy. Large polymers such as starch are partially hydrolyzed in the mouth by the enzyme amylase before being cleaved further into sugars. Many mammals have seen great expansions in the copy number of the amylase gene. These duplications allow for the pancreatic amylase AMY2 to re-target to the salivary glands, allowing animals to detect starch by taste and to digest starch more efficiently and in higher quantities. This has happened independently in mice, rats, dogs, pigs, and most importantly, humans after the agricultural revolution. Following the agricultural revolution 12,000 years ago, human diet began to shift more to plant and animal domestication in place of gathering and hunting. Starch has become a staple of the human diet. Despite the obvious benefits, early humans did not possess salivary amylase, a trend that is also seen in evolutionary relatives of the human, such as chimpanzees and bonobos, who possess either one or no copies of the gene responsible for producing salivary amylase. UsesAmylases are used in breadmaking and to break down complex sugars, such as starch (found in flour), into simple sugars. Yeast then feeds on these simple sugars and converts it into the waste products of ethanol and carbon dioxide. This imparts flavor and causes the bread to rise. While amylases are found naturally in yeast cells, it takes time for the yeast to produce enough of these enzymes to break down significant quantities of starch in the bread. This is the reason for long fermented doughs such as sourdough. Modern breadmaking techniques have included amylases (often in the form of malted barley) into bread improver, thereby making the process faster and more practical for commercial use. α-Amylase is often listed as an ingredient on commercially package-milled flour. Bakers with long exposure to amylase-enriched flour are at risk of developing dermatitis or asthma.Uses in Molecular biologyIn molecular biology, the presence of amylase can serve as an additional method of selecting for successful integration of a reporter construct in addition to antibiotic resistance. As reporter genes are flanked by homologous regions of the structural gene for amylase, successful integration will disrupt the amylase gene and prevent starch degradation, which is easily detectable through iodine staining.Medical usesAmylase also has medical applications in the use of pancreatic enzyme replacement therapy (PERT). It is one of the components in Sollpura (liprotamase) to help in the breakdown of saccharides into simple sugars. OthersAn inhibitor of alpha-amylase, called phaseolamin, has been tested as a potential diet aid. When used as a food additive, amylase has E number E1100, and may be derived from pig pancreas or mold fungi. Bacilliary amylase is also used in clothing and dishwasher detergents to dissolve starches from fabrics and dishes. Factory workers who work with amylase for any of the above uses are at increased risk of occupational asthma. Five to nine percent of bakers have a positive skin test, and a fourth to a third of bakers with breathing problems are hypersensitive to amylase. DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.  HyperamylasemiaBlood serum amylase may be measured for purposes of medical diagnosis. A higher than normal concentration may reflect one of several medical conditions, including acute inflammation of the pancreas (it may be measured concurrently with the more specific lipase), but also perforated peptic ulcer, torsion of an ovarian cyst, strangulation, ileus, mesenteric ischemia, macroamylasemia and mumps. Amylase may be measured in other body fluids, including urine and peritoneal fluid. A January 2007 study from Washington University in St. Louis suggests that saliva tests of the enzyme could be used to indicate sleep deficits, as the enzyme increases its activity in correlation with the length of time a subject has been deprived of sleep.How to take digestive enzymes: They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates. Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria(. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time.  How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.               <h1>Protease</h1> Description:A protease (also called a peptidase or proteinase) is an enzyme that catalyzes (increases the rate of) proteolysis, the breakdown of proteins into smaller polypeptides or single amino acids. They do this by cleaving the peptide bonds within proteins by hydrolysis, a reaction where water breaks bonds. Proteases are involved in many biological functions, including digestion of ingested proteins, protein catabolism (breakdown of old proteins), and cell signaling. Without additional helping mechanisms, proteolysis would be very slow, taking hundreds of years. Proteases can be found in all forms of life and viruses. They have independently evolved multiple times, and different classes of protease can perform the same reaction by completely different catalytic mechanisms. Biodiversity and sources of Proteases:Proteases occur in all organisms, from prokaryotes to eukaryotes to viruses. These enzymes are involved in a multitude of physiological reactions from simple digestion of food proteins to highly regulated cascades (e.g., the blood-clotting cascade, the complement system, apoptosis pathways, and the invertebrate prophenoloxidase-activating cascade). Proteases can either break specific peptide bonds (limited proteolysis), depending on the amino acid sequence of a protein, or completely break down a peptide to amino acids. The activity can be a destructive change (abolishing a protein’s function or digesting it to its principal components), it can be an activation of a function, or it can be a signal in a signalling pathway.PlantsProtease containing plant-solutions called vegetarian rennet has been in use for hundreds of years in Europe and middle-east for making kosher and halal Cheeses. Vegetarian rennet from Withania coagulans has been in use for thousands of years as Ayurvedic remedy for digestion and diabetes in the Indian subcontinent. It is also used to make Paneer. Plant genomes encode hundreds of proteases, largely of unknown function. Those with known function are largely involved in developmental regulation. Plant proteases also play a role in regulation of photosynthesis.AnimalsProteases are used throughout an organism for various metabolic processes. Acid proteases secreted into the stomach (such as pepsin) and serine proteases present in duodenum (trypsin and chymotrypsin) enable us to digest the protein in food. Proteases present in blood serum (thrombin, plasmin, Hageman factor, etc.) play important role in blood-clotting, as well as lysis of the clots, and the correct action of the immune system. Other proteases are present in leukocytes (elastase, cathepsin G) and play several different roles in metabolic control. Some snake venoms are also proteases, such as pit viper haemotoxin and interfere with the victim’s blood clotting cascade. Proteases determine the lifetime of other proteins playing important physiological role like hormones, antibodies, or other enzymes. This is one of the fastest “switching on” and “switching off” regulatory mechanisms in the physiology of an organism. By complex cooperative action the proteases may proceed as cascade reactions, which result in rapid and efficient amplification of an organism’s response to a physiological signal.BacteriaBacteria secrete proteases to hydrolyse the peptide bonds in proteins and therefore break the proteins down into their constituent amino acids. Bacterial and fungal proteases are particularly important to the global carbon and nitrogen cycles in the recycling of proteins, and such activity tends to be regulated by nutritional signals in these organisms. The net impact of nutritional regulation of protease activity among the thousands of species present in soil can be observed at the overall microbial community level as proteins are broken down in response to carbon, nitrogen, or sulfur limitation. Bacteria contain proteases responsible for general protein quality control (e.g. the AAA+ proteasome) by degrading unfolded or misfolded proteins. A secreted bacterial protease may also act as an exotoxin, and be an example of a virulence factor in bacterial pathogenesis (for example, exfoliative toxin). Bacterial exotoxic proteases destroy extracellular structures.VirusesSome viruses express their entire genome as one massive polyprotein and use a protease to cleave this into functional units (e.g. polio, norovirus, and TEV proteases). These proteases (e.g. TEV protease) have high specificity and only cleave a very restricted set of substrate sequences. They are therefore a common target for protease inhibitors. Uses:The field of protease research is enormous. Since 2004, approximately 8000 papers related to this field were published each year. Proteases are used in industry, medicine and as a basic biological research tool. Digestive proteases are part of many laundry detergents and are also used extensively in the bread industry in bread improver. A variety of proteases are used medically both for their native function (e.g. controlling blood clotting) or for completely artificial functions (e.g. for the targeted degradation of pathogenic proteins). Highly specific proteases such as TEV protease and thrombin are commonly used to cleave fusion proteins and affinity tags in a controlled fashion.Protease is also capable of medical applications. It is one of the enzymes in Sollpura (Liprotamase), a pancreatic enzyme replacement therapy (PERT). It assists in the breakdown of proteins into amino acids and polypeptides.Bromelain is a protease usually obtained from pineapple stem tissue, which has been medically used for its anti-inflammatory effects.Serratia E-15 protease (also known as serratiopeptidase or serrapeptidase) is another protease that has been proposed as an anti-inflammatory agent. Anti-inflammatory effects of this protease have been reported again more recently, and the material has come into some use in alternative or complementary medicine. On the other hand, it does not appear that there are positive clinical trial results for this material of a kind that would be needed to gain regulatory approval for controlled pharmaceutical uses.DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.How to take digestive enzymes: They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates. Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.   <h1>Glucoamylase</h1> Description:Glucoamylase (also known as amyloglucosidase or AMG) is an important digestive enzyme that helps us absorb nutrients and create energy from some of the most common plant foods that we eat. It does this by breaking down the starch that occurs naturally in most vegetables that we eat. This starch is present in high amounts in common foods like potatoes, corn, rice, and wheat. It’s also added as a filler or processing additive in prepared food products. All starch is formed of individual glucose molecules connected in a polysaccharide (poly=many saccharide = sugar). Glucoamylase cleaves or breaks off a glucose molecule from the end of starch polysaccharide molecules. It can also break apart disaccharides (2-sugar molecules) like maltose. The glucose molecule that is freed can then be used as a source of energy for the body. Humans and other animals produce glucoamylase produced in the mouth and pancreas, but it may also be derived from non-animal sources. Glucoamylase is often described separately from amylase because it digests starches by removing a glucose molecule from the end of polysaccharide rather than cleaving longer strings of glucose molecules in the middle, forming smaller chains. Specifically, this enzyme acts on the alpha-glycosidic bonds between glucose molecules in a polysaccharide. Note, glucoamylase cannot cleave the beta-bonds between glucose molecules of cellulose, which is another type of starch found in plants and commonly called fiber.Glucoamylase is one of the oldest and widely used biocatalysts in food industry. The major application of glucoamylase is the saccharification of partially processed starch/dextrin to glucose, which is an essential substrate for numerous fermentation processes and a range of food and beverage industries. Glucoamylase for commercial purposes has traditionally been produced employing filamentous fungi, although a diverse group of microorganisms is reported to produce glucoamylase, since they secrete large quantities of the enzyme extracellularly. The commercially used fungal glucoamylases have certain limitations such as moderate thermostability, acidic pH requirement, and slow catalytic activity that increase the process cost. Consequently, the search for newer glucoamylases and protein engineering to improve pH and temperature optima leading to amelioration in catalytic efficiency of existing enzymes have been the major areas of research over the years. The present review focuses attention on the recent advances in molecular biology and protein engineering of glucoamylase to improve its production and functional properties including the so far success achieved in isolating mutants with enhanced thermostability and selectivity, higher pH optimum and improved catalytic activity. Uses:Every day, the typical human consumes large amounts of starches, and while these carbohydrates have some nutritional value, they cannot be absorbed or digested by the body without the help of enzymes. Glucoamylase is one of several digestive enzymes that can break down these starches into glucose, which is usable by the body. This encourages smooth digestion and may help deter common digestive upsets such as heaviness, lethargy, bloating, gas and loose stools. Here are some of the health benefits of glucoamylase. 1. Eases Irritable Bowel SyndromeGlucoamylase, when combined with other enzymes may ease the negative effects of irritable bowel syndrome (IBS). One double-blind, crossover study shows the efficacy of enzymes like glucoamylase in optimizing digestion. Healthy participants who ate a high-calorie, high-fat meal took digestive enzymes, and other placebo group participants did not. Their gastrointestinal symptoms were recorded over a period of 17 hours, and it was found that people taking the enzymes had a statistically significant reduction in bloating, flatulence, and the sensation of fullness. The researchers suggested that because of these results, digestive enzymes may help IBS.  2. Helps Digestive Upset & Gastrointestinal IssuesMany people take digestive enzyme supplements and describe the effect as a little efficiency boost to their digestive system. There are many anecdotal reports of people experiencing smoother digestion, less sensitivity to foods that may typically “not agree” with them, and an improvement in gastrointestinal issues from supplementing with digestive enzymes. Commonly cited benefits include a reduction of symptoms like nausea, vomiting, gas, heartburn, bloating and loss of appetite.3. Supports the Immune SystemStudies show that glucoamylase combined with other enzymes can promote a normal autoimmunity response. In the case of autoimmune disorders, antigens, and antibodies, when not cleared out over time, can create tissue damage in the body. This can lead to diseases such as rheumatoid arthritis, lupus, and some types of kidney disease. While not a disease preventative, research suggests that enzymes can influence the immune system in beneficial ways.4. May Help Digestive OrgansStudies show a clear link that supplemental enzymes reduce the load on digestive organs. Animal experiments show that enzymes create healthier intestinal health and better nutrient absorption capacities.  5. Encourages Normal Blood Sugar BalanceA 2009 study published in the Journal of Nutrition found that glucoamylase plays a key role in starch digestion and in balancing blood sugar around meals in laboratory mice. Removing the gene needed for starch digestion in mice led to 40% higher blood glucose levels after a meal. Glucoamylase specifically plays a role in breaking down glucose from food.  DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.How to take digestive enzymes: They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates. Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.           <h1>Alpha-glucosidase</h1> Description:Alpha-glucosidase is a glucosidase located in the brush border of the small intestine that acts upon α(1→4) bonds. This is in contrast to beta-glucosidase. Alpha-glucosidase breaks down starch and disaccharides to glucose. Maltase, a similar enzyme that cleaves maltose, is nearly functionally equivalent.Glucosidase enzymes catalyze hydrolysis of starch to simple sugars. In humans, these enzymes aid digestion of dietary carbohydrates and starches to produce glucose for intestinal absorption, which in turn, leads to increase in blood glucose levels. Inhibiting the function of these enzymes in patients with type-2 diabetes may reduce hyperglycemia. Glucosidases are named on the basis of their substrates, types of linkages hydrolyzed, and precise mechanism of action. Alpha amylases (e.g., salivary and pancreatic alpha amylases) act on long chain carbohydrates, while alpha glucosidases (e.g., maltase glucoamylase and sucrase isomaltase) act on shorter starch chains and disaccharides to produce glucose.In the human digestive system, multiple glucosidases (carbohydrate digesting enzymes) coordinate breakdown of dietary starches and other polysaccharides to release glucose.Alpha glucosidases: Products of amylase hydrolysis cannot be absorbed by the intestine, so they are further broken down into simpler sugars or monosaccharides (e.g., glucose, galactose, and fructose) by small membrane-bound intestinal enzymes.DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.  How to take digestive enzymes: They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates. Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing.   How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.    Cellulase Description:Cellulase is any of several enzymes produced chiefly by fungi, bacteria, and protozoans that catalyze cellulolysis, the decomposition of cellulose and of some related polysaccharides. The name is also used for any naturally occurring mixture or complex of various such enzymes, that act serially or synergistically to decompose cellulosic material. Cellulases break down the cellulose molecule into monosaccharides (“simple sugars”) such as beta-glucose, or shorter polysaccharides and oligosaccharides. Cellulose breakdown is of considerable economic importance, because it makes a major constituent of plants available for consumption and use in chemical reactions. The specific reaction involved is the hydrolysis of the 1,4-beta-D-glycosidic linkages in cellulose, hemicellulose, lichenin, and cereal beta-D-glucans. Because cellulose molecules bind strongly to each other, cellulolysis is relatively difficult compared to the breakdown of other polysaccharides such as starch. Most mammals have only very limited ability to digest dietary fibers like cellulose by themselves. In many herbivorous animals such as ruminants like cattle and sheep and horses, cellulases are produced by symbiotic bacteria. Endogenous cellulases are produced by a few types of metazoan animals, such as some termites, snails, and earthworms.Uses:Cellulase is used for commercial food processing in coffee. It performs hydrolysis of cellulose during drying of beans. Furthermore, cellulases are widely used in textile industry and in laundry detergents. They have also been used in the pulp and paper industry for various purposes, and they are even used for pharmaceutical applications. Cellulase is used in the fermentation of biomass into biofuels, although this process is relatively experimental at present. Medically, Cellulase is used as a treatment for phytobezoars, a form of cellulose bezoar found in the human stomach, and it has exhibited efficacy in degrading polymicrobial bacterial biofilms by hydrolyzing the β(1-4) glycosidic linkages within the structural, matrix exopolysaccharides of the extracellular polymeric substance (EPS).DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer. Side Effects:Diarrhea, abdominal pain/cramps, or nausea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: severe abdominal discomfort, frequent/painful urination, joint pain. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Precautions:Before taking this digestive enzyme, tell your doctor or pharmacist if you are allergic to it; or to pork protein; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: sudden/severe swelling of the pancreas (acute pancreatitis), sudden worsening of long-term disease of the pancreas. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding. How to take digestive enzymes: They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates. Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing.How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.       <h1>Lipase</h1> Description:A lipase is any enzyme that catalyzes the hydrolysis of fats (lipids). Lipases are a subclass of the esterases. Lipases perform essential roles in digestion, transport and processing of dietary lipids (e.g. triglycerides, fats, oils) in most, if not all, living organisms. Genes encoding lipases are even present in certain viruses. Most lipases act at a specific position on the glycerol backbone of a lipid substrate (A1, A2 or A3)(small intestine). For example, human pancreatic lipase (HPL), which is the main enzyme that breaks down dietary fats in the human digestive system, converts triglyceride substrates found in ingested oils to monoglycerides and two fatty acids. Several other types of lipase activities exist in nature, such as phospholipases and sphingomyelinases; however, these are usually treated separately from “conventional” lipases. Some lipases are expressed and secreted by pathogenic organisms during an infection. In particular, Candida albicans has many different lipases, possibly reflecting broad-lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue.Initial lipase digestion occurs in the lumen (interior) of the small intestine. Bile salts reduce the surface tension of the fat droplets so that the lipases can attack the triglyceride molecules. The fatty acid and glycerol molecules are then taken up into the epithelial cells that line the intestinal wall, where they are resynthesized into triglycerides for transport to muscles and adipose tissues. At these sites lipases in the bloodstream hydrolyze the triglycerides, and the resulting fatty acids and glycerol are taken up by the cells of these tissues. In the adipose tissues triglycerides are re-formed for storage until the energy needs of the animal increase under conditions of stress or exercise. Lipases in the cells of adipose tissues break down the triglycerides so that fatty acids can reenter the bloodstream for transport to energy-requiring tissues. Uses:Lipases serve important roles in human practices as ancient as yogurt and cheese fermentation. However, lipases are also being exploited as cheap and versatile catalysts to degrade lipids in more modern applications. For instance, a biotechnology company has brought recombinant lipase enzymes to market for use in applications such as baking, laundry detergents and even as biocatalysts in alternative energy strategies to convert vegetable oil into fuel. High enzyme activity lipase can replace traditional catalyst in processing biodiesel, as this enzyme replaces chemicals in a process which is otherwise highly energy intensive, and can be more environmentally friendly and safe. Industrial application of lipases requires process intensification for continuous processing using tools like continuous flow microreactors at small scale. Lipases are generally animal sourced, but can also be sourced microbially.Blood tests for lipase may be used to help investigate and diagnose acute pancreatitis and other disorders of the pancreas. Measured serum lipase values may vary depending on the method of analysis. Lipase can also assist in the breakdown of fats into lipids in those undergoing pancreatic enzyme replacement therapy (PERT). It is a key component in Sollpura (Liprotamase).DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.  How to take digestive enzymes: They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates. Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.   Lactase Description:Lactase is an enzyme produced by many organisms. It is located in the brush border of the small intestine of humans and other mammals. Lactase is essential to the complete digestion of whole milk; it breaks down lactose, a sugar which gives milk its sweetness. Lacking lactase, a person consuming dairy products may experience the symptoms of lactose intolerance. Lactase can be purchased as a food supplement, and is added to milk to produce “lactose-free” milk products. Lactase (also known as lactase-phlorizin hydrolase, or LPH), a part of the β-galactosidase family of enzymes, is a glycoside hydrolase involved in the hydrolysis of the disaccharide lactose into constituent galactose and glucose monomers. Lactase is present predominantly along the brush border membrane of the differentiated enterocytes lining the villi of the small intestine. In humans, lactase is encoded by the LCT gene. Uses:This product is an enzyme supplement used to help people who have trouble digesting milk and other dairy products (lactose intolerance). Lactose is a type of sugar found in milk products. Lactase enzyme is normally produced by the body to help break down (digest) lactose. Lactose intolerance occurs when the body produces low amounts of lactase enzyme. Lactose intolerance can begin at different ages. Infants are not usually affected, but lactose intolerance can affect children as young as 2. It is very common in adults. One way to treat lactose intolerance is to avoid milk products. However, this can result in a lack of important nutrients and vitamins such as calcium, vitamin D, riboflavin, and protein. Some people use lactose-free milk or milk substitutes such as soy or rice milk. Most people with low lactase enzyme levels can tolerate small amounts of milk products at one time (2-4 ounces) and get symptoms only with larger servings (6 ounces or more). Taking lactase enzyme with milk products as directed can help prevent upset stomach, abdominal bloating/cramping, gas, and diarrhea caused by these products. The FDA has not reviewed this product for safety or effectiveness. Consult your doctor or pharmacist for more details.Food useLactase is an enzyme that some people are unable to produce in their small intestine. Without it they cannot break down the natural lactose in milk, leaving them with diarrhea, gas and bloating when drinking regular milk. Technology to produce lactose-free milk, ice cream and yogurt was developed by the USDA Agricultural Research Service in 1985. This technology is used to add lactase to milk, thereby hydrolyzing the lactose naturally found in milk, leaving it slightly sweet but digestible by everyone. Without lactase, lactose intolerant people pass the lactose undigested to the colon where bacteria break it down, creating carbon dioxide and that leads to bloating and flatulence.  DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.  How to take digestive enzymes: They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates. Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.   <h1>Beta Glucanase</h1> Description:Beta Glucanase is an enzyme that hydrolyzes β-glucans. The most important β-glucanases for brewing are those that break down the β-glucans located in the cell walls of the barley endosperm. High levels of β-glucans in brewing raw materials are to be avoided as they can cause problems, particularly in wort production and beer filtration. β-Glucanases are important in that they are needed to break down the complex β-glucan molecules to smaller units. There is a wide range of such enzymes, differing in the specific bonds that are broken.Benefits:People suffering from an overgrowth of the candida fungus (a condition also known as candidiasis) may benefit from taking beta-glucanase. Although it is a fungus or yeast infection, it is notoriously difficult to eliminate because of its inherent ability to resist antimicrobial agents. Sadly, many people treat digestive concerns and infections with prolonged and high-dose antibiotics. This can actually increase Candida’s ability to become even more antibiotic-resistant. Beta-glucanase is an enzyme that has been found to be particularly useful in reducing the coating or biofilm of Candida that can grow in the digestive tract. When an overabundance of beta-glucan is secreted by gut bacteria or candidal cells, there is a build up of biofilms within the organism. Science is currently looking into the link between these biofilms, the overgrowth of fungal organisms, as well as increased fungal resistance to drug therapy. The build up of excess beta-glucans has also been linked to increased antibiotic resistance.In-vitro and In-vivo studies on Candida biofilms show that when we have more beta-glucanase in the system, the Candida becomes significantly more susceptible to fungal cleansing agents. Perhaps more important, research has also shown that just supplementing with beta-glucanase alone reduces Candida biofilm in the gut. These preliminary scientific findings suggest that beta-glucanase may help reduce some of the challenging symptoms associated with having excess Candida in the intestinal tract. A great number of studies on enzymes have been conducted in Europe and Russia on actual human participants. The great majority suggests that a broad-spectrum enzyme preparation containing beta-glucanse can improve overall digestion and reduce a large amount of negative gastrointestinal issues. One fascinating, as yet unpublished trial done by a commercial enzyme manufacturer looked into the use of a beta glucanase-containing multi-enzyme preparation and its effects on carbohydrate and protein digestive capacities. The scientists created a gastrointestinal model for human digestion, including both the stomach and small intestinal tract, in an effort to quantitatively measure enzyme efficiency and effects. It was found that the meals taken with digestive enzymes, in optimal digestive conditions, significantly improved carbohydrate digestion and had a small improvement on protein digestion. Similarly, under conditions of less-than-optimal digestion, the multi-enzyme preparation greatly improved both carbohydrate and protein digestion.  DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.How to take digestive enzymes:They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates.Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing.How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.   <h1>Maltase</h1> Description:Found in people, yeasts, bacteria and plants, maltase is an enzyme that can break down disaccharide maltose. It can digest disaccharides into malt sugars also known as monosaccharides. Throughout digestion, starch is being converted in maltose by salivary or pancreatic enzymes also known as amylases. Afterwards, the maltase that is secreted will be transformed into glucose. Upon production, the glucose can be either used by the human body or stored within the liver as animal starch or glycogen. Even though the enzyme can be easily included in people’s diets, it is also believed to be produced in the human body by a mucus casing within the intestinal wall. When starch is ingested, the enzyme is digested only partially and converted in maltose by the pancreatic enzymes and the saliva enzymes. Maltese is also a carbohydrate-digesting enzyme that can be found naturally in sugars produced by the body when it breaks down starch. Additionally, it is a by-product when it comes to consuming sugar throughout several cooking processes, particularly during burning at high temperatures when the sugar changes colors from white to brown. Maltese is known to break down disaccharide maltose in 2 glucose molecules easily oxidized by the body in exchange for energy. Simply put, maltase is really important when it comes to the overall enzymatic process because it is used efficiently by the body to digest sugars and starch found under the shape of grains and other foods based on grains that we consume daily. Benefits:Maltase is known as an essential digestive enzyme found in people’s mouths and saliva. It can ease digestion within the small intestine and the pancreas. The lack of maltase within the system might cause problems because the small intestine will have a more difficult job in breaking down starches and sugars. Thus, the enzyme can be of great help for the whole digestive system. It can help people benefit from a smooth bowel digestion. Used within mucus membranes, the enzyme is included in the interior intestinal wall. Because it is located in the mouth, maltase works together with additional digestive carbohydrate enzymes to make sugars and starches simpler to digest. The process is halted and temporary reduced throughout more acidic digestion phases within the stomach; however, it is also resumed within the neutral pH of small intestines where maltase will be again secreted. The enzyme’s vegetarian form is created through a natural process of fermentation known as Aspergillis oryzae. Maltase is an enzyme that can also stop and support chronic diarrhea. Several studies performed on patients suffering from diarrhea showed that enzyme deficiency triggered the condition. In addition, the lack of important enzymes within the body might lead to chronic diarrhea and the only remedy would be ingesting supplement rich in enzymes in order to reduce inflammation, infections and mucosal secretions in the gut. Maltase breaks down grain and it is shaped in a way where it can easily break the connection and set free the 2 glucoses pieces that are linked together. Hence, it can split maltose molecules extremely fast and efficiently.Maltase can work as a support and preventive mechanism for various digestive complaints in kids who suffer from autism. Advanced technology has managed to develop tremendously and thus, the use of enzymes like maltase could have beneficial effects. Several research studies have confirmed that numerous kids with autism showed a correlation in decreased intestinal disaccharide commotion. This is connected to the existence of digestive enzymes such as maltase within the gut. Mainly because autistic kids have lower amounts of maltase, research studies are now considering providing maltase enzymes to ease their symptoms. Another study showcased that 18 of 36 autistic kids had gastrointestinal disorders because of the lack of digestive enzymes within the gut. Also, biopsies have shown that the same kids were suffering from chronic stomach inflammation, which is another common symptom when enzymes are lacking from the body.Nowadays, medicine has managed to advance tremendously. Hence, research scientists have finally understood the link between the digestive system and genetics. Chronic diarrhea left untreated might have severe side effects later on in the future. Throughout life, the digestive imbalance might worsen and thus people might experience serious gut abnormalities. People who lack enzymes cannot break down properly disaccharide sucrose. Several research studies have shown that fungal derived maltase has amazing clinical improvement in kids and adults with challenging digestive problems. Infantile, or type A acid maltase deficiency normally starts showing symptoms at the ages of 5 months until 2 years old. Childhood or type B acid maltase deficiency normally starts showing visible symptoms in early childhood at the age of 7-8 years old. The last type of deficiency is type C or adult and it highlights side effects around the age of 30-40. AMD or acid maltase deficiency is additionally known as pompe disease which is a genetic condition that can affect proper muscle function. Passed from parents to their kids, the mutation is called acid alph-glucosidae and can cause a certain substance known as glycogen to boost within the muscles of AMD patients. The chemical substance known as acid maltase regulates glycogen stored within muscle cells. The moment the muscle cell accumulates too much glycogen, acid maltase is being released to break down the surplus. AMD is thought to affect around 40,000 births and the sooner is spotted the better for the child. In general, more severe symptoms appear after 10-20 years. As of April 2006, the Food and Drug Administration in the US approved Myozyme as an enzyme therapy replacement for patients with lack of maltase in their bodies. Results were quite positive and the condition of most patients was really improved.  DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.How to take digestive enzymes:They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates.Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.   <h1>Xylanase</h1> Description:Xylanase is any of a class of enzymes that degrade the linear polysaccharide xylan into xylose, thus breaking down hemicellulose, one of the major components of plant cell walls. As such, it plays a major role in micro-organisms thriving on plant sources for the degradation of plant matter into usable nutrients. Xylanases are produced by fungi, bacteria, yeast, marine algae, protozoans, snails, crustaceans, insect, seeds, etc.; mammals do not produce xylanases. However, the principal commercial source of xylanases is filamentous fungi. Commercial applications for xylanase include the chlorine-free bleaching of wood pulp prior to the papermaking process, and the increased digestibility of silage (in this aspect, it is also used for fermentative composting). Apart from its use in the pulp and paper industry, xylanases are also used as food additives to poultry; in wheat flour for improving dough handling and quality of baked products; for the extraction of coffee, plant oils, and starch; in the improvement of nutritional properties of agricultural silage and grain feed; and in combination with pectinase and cellulase for clarification of fruit juices and degumming of plant fiber sources such as flax, hemp, jute, and ramie. A good quantity of scientific literature is available on key features of xylanase enzymes in biotechnology ranging from their screening in microbial sources to production methods, characterization, purification and applications in commercial sector. These enzymes are used to improve the dough’s workability and absorption of water. In the future, xylanase may be used for the production of biofuel from unusable plant material. Uses:As a concentrated source of cellulose degrading enzymes for use as an animal feed additive, in industrial applications, sanitary applications such as waste paper degradation and as in a variety of textile processing applications. Other applications include detergents, pre-spotters and industrial cleaning compounds. This product is currently being used in Biobleaching applications for wood pulp in papermills to reduce AOX emissions. DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer. Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.How to take digestive enzymes:They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates.Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.   <h1>Pectinase</h1> Description:Pectinase is an enzyme that breaks down pectin, a polysaccharide found in plant cell walls. Commonly referred to as pectic enzymes, they include pectolyase, pectozyme, and polygalacturonase, one of the most studied and widely used commercial pectinases. It is useful because pectin is the jelly-like matrix which helps cement plant cells together and in which other cell wall components, such as cellulose fibrils, are embedded. Therefore, pectinase enzymes are commonly used in processes involving the degradation of plant materials, such as speeding up the extraction of fruit juice from fruit, including apples and sapota. Pectinases have also been used in wine production since the 1960s. The function of pectinase in brewing is twofold, first it helps break down the plant (typically fruit) material and so helps the extraction of flavours from the mash. Secondly the presence of pectin in finished wine causes a haze or slight cloudiness. Pectinase is used to break this down and so clear the wine. They can be extracted from fungi such as Aspergillus niger. The fungus produces these enzymes to break down the middle lamella in plants so that it can extract nutrients from the plant tissues and insert fungal hyphae. If pectinase is boiled it is denatured (unfolded) making it harder to connect with the pectin at the active site, and produce as much juice. Addition of chelating agents or pretreatment of the plant material with acid enhance the effect of the enzyme. Uses:Pectinase enzymes are used for extracting juice from purée. This is done when the enzyme pectinase breaks down the substrate pectin and the juice is extracted. The enzyme pectinase lowers the activation energy needed for the juice to be produced and catalyzes the reaction. DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.   Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.How to take digestive enzymes:They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates.Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.   <h1>Phytase</h1> Description:Phytase is known to be an enzyme that can liberate mineral residues and phosphate from the phytic acid, also named phytate which is a compound made throughout the process maturation of grains and plant seeds. About 2/3 of phosphorus is present within plant-based foods like wheat, grains and cereal. Minerals like magnesium, zinc, calcium and iron are typically known to be charged with positive ions within phosphate. Additionally, magnesium, calcium, iron and zinc are liberated which makes these essential minerals much more available. Phytase is a necessary enzyme within the human body because it facilitates the digestive process and ensures bone health. Traditionally found in plants, phytase is an all-natural enzyme utilized for breaking down and boosting the nutritional value of legumes, corn, seeds and grains. Several studies have confirmed that using the enzyme can diminish the body’s needs or calcium phosphate and boost digestive wellbeing. Consequently, phytase is medically called myo-inositol-hexaphosphate phosphohydrolase, and it is produced either by certain microorganisms or already available in plants. It can break down phytic acid that cannot be digested by the body within oil seeds and grains. The increased molecular protein is delicate at high temperatures and thus, the product needs to be well taken care of and properly stored.Benefits:In nature people can find phytase in animals, plants and microorganisms. The primary foundation of the commercially available phytase is known to be fungal, even though yeast phytase and bacterial have been additionally discovered. Phytase was considered a medical breakthrough back in the 90s when it used to be the key driver for reducing phosphorus excretions in poultry and pigs. The enzyme can now boost digestibility, protein and amino acid accumulation. Phytase can also: Decrease phytic acid within the body, Boost mineral bioavailability and absorption, trim down mineral deficiency, Reduce toxic build-up within the digestive tract, Increase bone health, Hew bound phosphorus within the human body.Several research studies have demonstrated that phytase can assimilate and absorb crucial minerals such as iron, calcium and magnesium. The enzyme can also reduce detrimental outcomes of phytic acid present in the system. A lot of plants that we consume on a daily basis like soybeans, cereals, seeds and corn have high levels of acid in their composition. These types of can decrease people’s ability to absorb certain types of nutrients. Thus, the insoluble complexes within these kinds of minerals are negatively identified as phytic acid that has the potential to positively charge molecules in proteins and minerals. At the Federal Centre of Food and Nutrition in Germany, there was another research study going on. It was meant to uncover if phytase supplements could create powerful increases in the reduction and uptake of phytate content in minerals found in legume derived products and cereals. Aspergillus, a phytase fungus was believed to contain a pH level with a minimum percentage of 80 from the maximum pH values. The study showed that phytase supplements had a pretty promising application for people’s digestion, especially for intestinal alkaline phosphatase in humans. The phytase enzyme could additionally reduce deficiency in minerals for groups that are more vulnerable like vegans, child bearing women and vegetarians. The enzyme can also decrease toxic accumulations within the digestive tract. Mainly because phytase breaks down the phytic acid within the system, people’s digestive processes have fewer chances to build up excessive amounts of insoluble compounds within the digestive tract. The enzyme can also break down various forms of phosphorus and it can aid people absorb iron and minerals so much better. Phytase is a great digestive enzyme that prevents bone loss and reduces osteoporosis. As most people already know, phosphorus is an elementary compound which protects bones and helps them grow properly. At the Auburn University scientists looked into the final effects of the enzyme. They’ve tried to highlight its action on people’s digestion.Phytase is an enzyme that hydrolyzes in-feed phytate, releases digestible phosphorus and facilitates the utilization of phosphorus in the feeding process of animals. In can also improve bio-availability of several nutrients like proteins and minerals, thus improving animal production performance. The enzyme reduces the assimilation of fluorin and heavy metals within the system. It has been characterized and isolated from certain types of cereals such as maize, barley, rice and wheat, as well as beans like dwarf and mung beans. The activity of phytase has been detected in potatoes, white mustard spinach, lettuce, lily pollen and grass. The optimum level of the enzyme’s pH ranges from 2.2 to 8. Microbial phytases with a fungal origin have a different pH level that varies from 4.5 to 5.6. Over the years studies have tried to demonstrate that the enzyme can successfully reduce protein, lipid and starch digestibility. Phytase forms protein complexes with both alkaline and acidic pH. This mixture might affect protein changes in structure that might decrease protein solubility and enzymatic activity. Utilized as animal supplement feed, the enzyme enhances nutritive value through the liberation of inorganic phosphate from the famous phytic acid. Phytase could be additionally purified from the body’s transgenic microbes. It has been recently produce in alfalfa, rice plants and transgenic canola. The United States is the primary market place to feed phosphates which is an important additive for growing strong and healthy animals. The phytase marketplace is estimated at $200 million and the rate keeps growing each year with 5%. All in all, phytase is a digestive enzyme that is produced by a certain bacteria found within the ruminant gut of animals like sheep and cattle. Non-ruminants, or better said, the people, bids and dogs don’t produce phytase but the enzyme can be found under the shape of supplements and it is known to boost proteins, carbohydrates, calcium and phosphorus. Boosted utilization of phosphorus, as well as decreased inorganic phosphorus within a diet will result in much less excretion from animals like pigs. The enzyme can boost minerals and it must be treated with care because it cannot tolerate high temperatures and humidity. DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.  Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.How to take digestive enzymes:They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates.Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing. How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.                <h1>Invertase</h1> Description:Invertase is a digestive enzyme that separates sucrose into its main components, fructose and glucose. Usually derived from Saccharomyces cerevisiae and afterwards purified to be utilized alone or within a multi-enzyme formula, invertase is mixed up with some other carbohydrates to enhance overall starch and sugar digestion. The ability of invertase to hydrolyze the connection between glucose and fructose makes the enzyme an important part of the digestive process. Additionally known as beta-fructofuranosidase, invertase is considered an essential enzyme that can easily help people digest sugars. It can be found in yeast sources and pollen as it has a key role not just in the digestive process but also in the overall prevention of human diseases. Invertase can also slow down the anti-aging progression and it can help people enjoy physical rejuvenation. When we get older we tend to have less access to the enzyme. Thus, step by step we decrease the ability to extract vital nutrients from foods that we consume on a daily basis. Invertase can additionally slow down the digestive process mostly because starches and sugars are such important components of the lives of the people. Although some carbohydrates have beneficial effects on the human body, others can’t be digested and absorbed well without asking for help from the invertase enzyme. Invertase can also split disaccharide sucrose in monosaccharide fructose and glucose. Thus, the enzyme is inhibited by increased concentrations of sucrose of invertase. At 60°C, the enzyme features optimum activity and a pH of 4.5 which can be usually adjusted when adding citric acid to a reaction mix.Benefits:Naturally created by common bees, who utilize their ability to hydrolyze sugars and turn it into raw nectar, invertase has a diverse potential to stay active within numerous ranges of pH levels. Honeybees can easily make massive volumes of enzymes because they break the connection between fructose and glucose, including hydroxide and hydrogen. Invertase can naturally boost people’s immune system. The enzyme can be found in honey and it has been studied over and over again. One particular research done on asparagus had managed to find that intense activity of invertase found in primary portions of asparagus might have direct connections to high metabolism. Consequently, the digestive enzyme has numerous anti-oxidant properties and it can also be a strong anti-microbial agent. These attributes allow it to help gut fermentation and prevent bacterial infestations because of oxidation. Years ago, in India honey had been used in patients who were having weak hearts. By taking honey they experienced less intestinal pain and all bacteria were eradicated. Invertase was additionally utilized for its hygroscopic properties, as well as for its ability to take out moisture from the system which could make erial infections subside. Simply because the enzyme can create pre-digested sugars, it can also reduce stomach toxicity and sugars won’t remain too long within the stomach to create toxic fermentation which can build up within the digestive tract. Therefore, invertase can keep the body far away from ulcers, as well as additional digestive ailments. The enzyme has antiseptic and antibacterial properties because in honey invertase shows the power to convert glucose into all-natural hydrogen peroxide antiseptics. Enzymes that contain invertase in their composition might also reduce flu and colds, as well as other respiratory infections. A detailed European study performed on over 18,000 patients, emphasized that honey could help tremendously upper tract infections in the respiratory system like asthma, allergies and bronchitis. Some other medical studies have shown that invertase has chemotherapeutic properties. A Japanese and Australian research study discovered that enzymes within honey could help them deal with their stomach and bone cancer so much better. In certain situations, the disease went into regression; at this point, therapy based on the enzyme’s properties is being utilized to make people who suffer from cancer have a better life. European studies have reported that invertase treatments can diminish adverse side effects caused by chemotherapy and radiotherapy. In several tumor types, the rate of survival can be lengthened especially because the systemic effect of the enzyme therapy is focused on anti-inflammatory potential. Invertase is additionally a standard food additive. Processed in foods like biscuits, chips and chewing gum, some of the side effects might include diabetes. Endless companies are using the additive in their products and it has become extremely popular on worldwide scale as well. Numerous microorganisms can produce invertase, and thus, use sucrose as a primary nutrient. The resulting product from fructose and glucose is known as sugar syrup and it is often included when baking. Additionally, it can be found in massive productions of sweets and candies because it has a sweeter taste than most types of average sugar on the market. When sucrose interacts with invertase, or with any other kind of table sugar, the hydrolysis process is being stimulated. Various candy companies and bakers use trimoline or inverted sugar syrup when baking. Unlike normal sucrose, invertase features a stronger taste; in addition, the syrup will not crystallize as hastily as normal sugar. The enzyme can also be found in sweets and candies that contain liquefied sugar center like cherries covered in chocolate for example. When it comes to marketing, the enzyme can be bought with various strengths namely, single, double, triple. While some types are in liquid form others come in the shape of powder that can be added in water. Because sucrose splits faster at high temperatures, invertase should be used at 60°C. DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm. How to take digestive enzymes:They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates. Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you. How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing.    How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you.   <h1>Hemicellulase</h1> Description:The hemicellulase enzyme breaks down hemicellulose, which is a type of cellulose and a key component of the cell wall in all plants. Different forms of plant hemicellulose include glucans, galactans, xylans, mannans and pentosans. Common fiber-rich breakfast cereals, for example, have a large amount of hemicelluloses (2 to 12%). Hemicellulase is needed to break down these fiber-rich components, and because it is not produced naturally in the human body, we rely on microorganisms that live in the human digestive tract to produce it for us. The hemicellulase enzyme has the ability to take non-cellulose polysaccharides (long chains of sugars) we eat and convert them into usable constituents. Hemicellulase, which is crucial for the breaking down of fruits, vegetables, and many grains is required to break down the “hard” hemicellulose carbohydrates, which are known to slow digestion and the absorption of various nutrients. If we eat large amounts of plant material but do not have enough hemicellulase, we get a very limited prebiotic intake. These prebiotics are composed of smaller indigestible saccharide units that serve as fuel for various types of probiotics (good bacteria) resident in the digestive tract. Uses:Hemicellulase possesses the distinct ability to boost this prebiotic activity. Specifically, common hemicellulose carbohydrates found in the food we eat every day are actually added to things like ice cream and dairy products. For this reason, it is important to provide your body with a prebiotic boost by taking a supplement containing hemicellulase. Hemicellulase is a fairly complex enzyme, and there are different permutations of hemicellulase. Different types of this enzyme have been used for different purposes in food technologies, particularly for its ability to enhance the quality of dough, as well as produce fruit juices and alcoholic beverages. In fact, it is a commonly-added enzyme in the production of wines, as the enzyme helps strip away the unwanted compounds from the skins of the grapes that might change the taste of the wine. Although plants make hemicellulases for growth and development, most of the commercial interest is in the enzymes produced by microorganisms.Benefits: 1. May Reduce CandidaSome research suggests that an increase in this enzyme can help prevent and reduce yeast infestations such as Candida. This is perhaps related to the fact that the cell wall of candida is composed of hemicellulose. Again, as hemicellulase digests hemicellulose, it may help in reducing Candida.  2. Better Digestive Capacity with AgingTaking digestive enzymes such as hemicellulase can counteract the net loss of enzymes that occurs with aging, whether due to a loss in pancreatic production of enzymes or a change in beneficial flora in the gut. Research supports this. In Japan, scientists have confirmed that intestinal enzyme output showed a gradual decrease with age. Individuals 65 years and older were tested, and women, in particular, were found to have the sharpest declines in enzyme health. 3. Improves Overall HealthAnimal studies suggest that supplementing with hemicellulase in feedings helps not only increase nutrient digestibility but also betters performance and boosts food conversion ratio. One 2005 study published in the Animal Science Journal found that hemicellulase could boost overall health. Hemicellulase enzyme supplements were given to chickens, and their subsequent nutrient utilization, performance, and digestion capacities were analyzed. It was found that the animals given enzymes grew faster, had decreased abdominal fat and energy content of the diet was improved by the mixed enzyme. This offers proof that hemicellulase has a synergistic effect on the performance and health in animals. More research on humans is needed within the scientific realm.DosageThe potency of proteolytic enzymes in supplemental form is expressed as milligrams or grams as well as in “activity units” or “international units.” These terms refer to the enzyme’s strength (particularly its potency/digestive power). The proper dosage varies from person to person (depending on age, overall health, and other factors). Therefore, it’s recommended to consult with a homeopathic doctor, or other health care provider, regarding the proper dose. Also, be sure to read the label instructions; it is not recommended to exceed the dosage suggested by the manufacturer.Side Effects:Side effects of digestive enzymes include: nausea, diarrhea, abdominal cramping, headache, neck pain, nasal congestion, swelling of the legs and feet, rash, dizziness, low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), diabetes mellitus exacerbation, gas (flatulence), indigestion, biliary tract stones, abnormal feces, fluid in the gallbladder, renal cyst, viral infection, asthma, inflammation of the stomach (gastritis), muscle spasm.How to take digestive enzymes:They shouldn’t be taken on empty stomach. Not if you want them to work properly. Digestive enzymes are literally designed to break down food, That’s their only job, and each one caters to a different type of molecule. So, taking your enzyme supplements on an empty stomach means they won’t have anything to kick them into action, unfortunately. No food means the enzymes have nothing to do. And that’s just boring. Be supplement smart! The best time to take your enzymes is right before, or right as you start eating. When in doubt, check the label. Usually anywhere from 30 minutes to right before you eat is ideal. And if you really want to maximize the efficiency of your supplements, take specific ones with their intended food. For example, take lactase when you’re eating or drinking dairy products, or amylase when eating carbohydrates.Can I Take Probiotics and Digestive Enzymes at the Same Time:You sure can. Probiotics and digestive enzymes are different things and do different things, so it’s totally OK to take them together. In fact, it’s a great idea — they work awesome as a team. Here’s how they’re complementary:Probiotics are live microorganisms and are generally described as the “good” bacteria in our gut. They help maintain the right balance of what’s called flora in our bodies (basically the mix of good and bad bacteria. They’re a part of an entire network in our bodies called our microbiome, which is tied to digestion, the immune system, mood balance, essential nutrient creation. And it plays a role in allergic reactions as well as viral, bacterial, fungal and yeast infections. Digestive enzymes, on the other hand, are long-chain proteins. They also work in your gut, but their job is to break down food so you can absorb the nutrients in what you eat. Think of them as catalysts to help your body digest things properly. They stimulate chemical reactions, many of which are crucial to breaking down food your both otherwise couldn’t. Different jobs, but both very important. So, go ahead and take your probiotics and enzymes at the same time! Your body will thank you.How Long Does It Take Them to Work:The great thing about digestive enzymes is all they need to start working is food. They’ll start to break down food molecules as soon as they come into contact with them. You should start to notice benefits within a few days! And remember: Your enzymes are only as good as what you feed them. In order to get the most out of them, make sure your diet is filled with nutrient-rich foods to help them do their thing.How Often Should I Take Them:Every day! If you’re experiencing chronic digestive issues like cramping, bloating, or gas, it usually means that your body is out of sorts — something isn’t working the way it’s supposed to. And often, problems in our guts manifest in unexpected ways like headaches, acne, and memory problems. When in doubt, look to your digestion. Your body, once it heals itself, will continue to naturally produce enzymes. So, taking supplements is just helping things out a bit. It can take upwards of 6 months for your gut to regulate itself, so taking your supplements daily is recommended. Basically, while they can be a smart addition to your meals, digestive enzymes aren’t meant to be a permanent part of your routine; once your body has recovered and your gut is able to produce a healthier number of enzymes naturally, you can start to take less. Talk to your doctor to figure out what’s right for you. </body>